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FCMAB317PE Milli-Mark™ Anti-NeuN-PE Antibody, clone A60

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FCMAB317PE
100 tests  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMPhycoerythrinMonoclonal Antibody
      Description
      Catalogue NumberFCMAB317PE
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-NeuN-PE Antibody, clone A60
      Alternate Names
      • Neuron-Specific Nuclear Protein
      • Neuna60
      • A60
      Background InformationNeuN antibody (NEUronal Nuclei; clone A60) specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei, perikarya and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples (Mullen et al., 1992; Wolf et al., 1996). Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuron (Mullen et al., 1992). Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5.
      Product Information
      FormatPhycoerythrin
      Control
      • U251 cells
      PresentationPurified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA
      Quality LevelMQ100
      Applications
      ApplicationThis Milli-Mark Anti-NeuN-PE Antibody, clone A60 is validated for use in FC for the detection of NeuN.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenPurified cell nuclei from mouse brain.
      CloneA60
      HostMouse
      SpecificityAntibody recognizes Neuronal Nuclei.
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • NeuN
      • A58
      Purification MethodProtein A Purfied
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using U251 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB317PE 04053252630286