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444255 MMP Inhibitor Set I - CAS 161314-17-6 - Calbiochem

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444255
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #
      161314-17-6
      Description
      Overview

      This product has been discontinued.



      Contains 5 mg each of MMP-2/MMP-9 Inhibitor I (Cat. No. 444241) and MMP-3 Inhibitor II (Cat. No. 444225), and 1 mg each of GM 6001 (Cat. No. 364205), GM 6001, Negative Control (Cat. No. 364210), and MMP-8 Inhibitor I (Cat. No. 444237).

      Catalogue Number444255
      Brand Family Calbiochem®
      Application Data
      References
      Product Information
      CAS number161314-17-6
      FormSolid
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      444255 0

      Documentation

      MMP Inhibitor Set I - CAS 161314-17-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      444255
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      Application Data
      DescriptionMatrix metalloproteinases (MMP) are a family of zinc-dependent enzymes that include interstitial collagenases, stromelysins, gelatinases, and membrane-type metalloproteinases. They are part of the intricate extracellular matrix (ECM) and are involved in maintaining the integrity of the ECM by removing undesired proteins. MMPs play a key role in the normal physiology of connective tissue during development, morphogenesis, and wound healing. However, the unregulated activity of MMPs has been implicated in a number of disease processes, including arthritis, tumor cell metastasis, and atherosclerosis. As a result of their involvement in various disease states, MMPs have become a target for the development of potential therapeutic inhibitors.

      The Calbiochem® brand has assembled a convenient set containing 4 inhibitors (and one negative control) with different specificities for the study of the biological activity of MMPs and the physiological mechanisms of MMP activation and inhibition.
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number161314-17-6
      Storage Protect from moisture
      Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Toxicity Standard Handling