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444225 MMP-3 Inhibitor II - CAS 161314-17-6 - Calbiochem

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
161314-17-6C₁₃H₂₀N₂O₅S

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444225-5MG
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      Description
      OverviewA potent and cell-permeable inhibitor of human MMP-3 (Ki = 130 nM).
      Catalogue Number444225
      Brand Family Calbiochem®
      SynonymsN-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
      References
      ReferencesKato, N., et al. 2002. Genome Informatics 13, 272.
      MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
      Product Information
      CAS number161314-17-6
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₃H₂₀N₂O₅S
      Chemical formulaC₁₃H₂₀N₂O₅S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targethuman MMP-3
      Primary Target K<sub>i</sub>130 nM against human MMP-3
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      444225-5MG 04055977205268

      Documentation

      MMP-3 Inhibitor II - CAS 161314-17-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      MMP-3 Inhibitor II - CAS 161314-17-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      444225

      References

      Reference overview
      Kato, N., et al. 2002. Genome Informatics 13, 272.
      MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      SynonymsN-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
      DescriptionA cell-permeable, potent inhibitor of human MMP-3 (stromelysin; Ki = 130 nM).
      FormWhite solid
      CAS number161314-17-6
      Chemical formulaC₁₃H₂₀N₂O₅S
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (30 mg/ml) or Ethanol (8 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesKato, N., et al. 2002. Genome Informatics 13, 272.
      MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Matrix Metalloproteinase (MMP) Inhibitors