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420305 K-252c - CAS 85753-43-1 - Calbiochem

A cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (IC₅₀ = 2.45 µM) and protein kinase A (IC₅₀ = 25.7 µM).

K-252c - CAS 85753-43-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: PKC
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420305
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
85753-43-1C₂₀H₁₃N₃O

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      Description
      OverviewA cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (IC50 = 2.45 µM) and protein kinase A (IC50 = 25.7 µM).
      Catalogue Number420305
      Brand Family Calbiochem®
      References
      ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
      Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.
      Product Information
      CAS number85753-43-1
      ATP CompetitiveY
      FormOff-white solid
      Hill FormulaC₂₀H₁₃N₃O
      Chemical formulaC₂₀H₁₃N₃O
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKC
      Primary Target IC<sub>50</sub>2.45 µM against protein kinase C
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      420305-1MG 04055977210927

      Documentation

      K-252c - CAS 85753-43-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      K-252c - CAS 85753-43-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      420305

      References

      Reference overview
      Fabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
      Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      DescriptionA cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (IC50 = 25.7 µM) and protein kinase C (IC50 = 2.45 µM).
      FormOff-white solid
      CAS number85753-43-1
      Chemical formulaC₂₀H₁₃N₃O
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml) or Methanol
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
      Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.