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407252 Insulin-Like Growth Factor-I, Mouse, Recombinant, E. coli

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407252
  
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      Overview

      Key Spec Table

      Purity
      ≥98% by SDS and HPLC
      Description
      Overview

      This product has been discontinued.



      Full-length, recombinant, mouse insulin-like growth factor I (IGF-I) expressed in E. coli. IGF-I regulates proliferation and survival signals through the Akt pathway. Mouse IGF-I shares 94% sequence identity with human IGF-I and exhibits cross-species reactivity. Useful in the study of cell proliferation and survival signals.

      Catalogue Number407252
      Brand Family Calbiochem®
      SynonymsmIGF-I
      References
      ReferencesClemmons, D.R., et al. 2006. Curr. Opin. in Pharmacol. 6, 620.
      Bell, G.I., et al. 1986. Nucleic Acids Res. 14, 7873.
      Product Information
      FormLyophilized
      FormulationSterile-filtered prior to lyophilization. Contains no additives.
      Quality LevelMQ100
      Biological Information
      Biological activityED₅₀: ≤2 ng/ml (corresponding to a specific activity of ≥1 x 10⁶ units/mg) as determined by a cell proliferation assay using FDC-P1 cells. For most in vitro applications IGF-I exerts is biological activity in the concentration range of 1-20 ng/ml.
      Purity≥98% by SDS and HPLC
      Physicochemical Information
      ContaminantsEndotoxin: ≤1 ng/µg IGF-I
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions. Aliquots may be stored at 4°C for up to 1 week without loss of biological activity.
      Global Trade Item Number
      Catalogue Number GTIN
      407252 0