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508437 InSolution™ Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

A 25 µM (10 mg/583 µL) sterile-filtered solution of Pepstatin A, Synthetic in DMSO.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Pepstatin A, Synthetic InSolution, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid

Primary Target: aspartic proteases
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508437
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
26305-03-3C₃₄H₆₃N₅O₉

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      		 Glass bottle 10 mg
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      Description
      Catalogue Number508437
      Brand Family Calbiochem®
      SynonymsPepstatin A, Synthetic InSolution, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
      References
      ReferencesIsahara, K., et al. 1999. Neuroscience 91, 233.
      Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
      Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
      Carraway, R.E., et al. 1991. Peptides 12, 107.
      Eid, M., et al. 1981. Biochem. J. 197, 465.
      Umezawa, H., et al. 1970. J. Antibiot. 23, 259.
      Product Information
      CAS number26305-03-3
      FormLiquid
      FormulationA 25 mM (10 mg/583 µL) sterile-filtered solution of Pepstatin A, Synthetic (Cat. No. 516481) in DMSO.
      Hill FormulaC₃₄H₆₃N₅O₉
      Chemical formulaC₃₄H₆₃N₅O₉
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetaspartic proteases
      Purity≥98% by HPLC
      Physicochemical Information
      Peptide SequenceIva-Val-Val-Sta-Ala-Sta
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 4 months at -20°C. Use only fresh DMSO for further dilutions.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.08437.0001 04055977261967

      Documentation

      InSolution™ Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Isahara, K., et al. 1999. Neuroscience 91, 233.
      Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
      Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
      Carraway, R.E., et al. 1991. Peptides 12, 107.
      Eid, M., et al. 1981. Biochem. J. 197, 465.
      Umezawa, H., et al. 1970. J. Antibiot. 23, 259.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-February-2017 JSW
      SynonymsPepstatin A, Synthetic InSolution, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
      DescriptionA reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cells. Effective concentration: 1 µM.
      FormLiquid
      FormulationA 25 mM (10 mg/583 µL) sterile-filtered solution of Pepstatin A, Synthetic (Cat. No. 516481) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number26305-03-3
      Chemical formulaC₃₄H₆₃N₅O₉
      Peptide SequenceIva-Val-Val-Sta-Ala-Sta
      Purity≥98% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 4 months at -20°C. Use only fresh DMSO for further dilutions.
      Toxicity Standard Handling
      ReferencesIsahara, K., et al. 1999. Neuroscience 91, 233.
      Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
      Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
      Carraway, R.E., et al. 1991. Peptides 12, 107.
      Eid, M., et al. 1981. Biochem. J. 197, 465.
      Umezawa, H., et al. 1970. J. Antibiot. 23, 259.