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402096 INDO 1/AM

Cell-permeable ester derivative of INDO 1.

INDO 1/AM MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Pentaacetoxymethyl Ester

402096
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      112926-02-0C₄₇H₅₁N₃O₂₂
      Description
      Overview

      This product has been discontinued.



      Cell-permeable ester derivative of INDO 1. After crossing the cell membrane, INDO 1/AM is rapidly hydrolyzed by cytoplasmic esterases and remains trapped within the cell. Can be used to selectively monitor Ca2+ levels in mitochondria and in the cytosol. It is insensitive to Mg2+. Note: 1 set = 10 x 100 µg.
      Catalogue Number402096
      Brand Family Calbiochem®
      Synonyms1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Pentaacetoxymethyl Ester
      References
      ReferencesZhou, Z., et al. 1998. J. Physiol. 507, 379.
      Griffiths, E.J., et al. 1997. Am. J. Physiol. 273, C37.
      Grierson, J.P., et al. 1992. J. Neurophysiol. 67, 704.
      Lopez, M., et al. 1989. Cytometry 10, 165.
      Product Information
      CAS number112926-02-0
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₄₇H₅₁N₃O₂₂
      Chemical formulaC₄₇H₅₁N₃O₂₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMonitor Ca2+ levels in mitochondria and in the cytosol
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Emission max.
      Excitation max.
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      402096 0

      Documentation

      INDO 1/AM SDS

      Title

      Safety Data Sheet (SDS) 

      INDO 1/AM Certificates of Analysis

      TitleLot Number
      402096

      References

      Reference overview
      Zhou, Z., et al. 1998. J. Physiol. 507, 379.
      Griffiths, E.J., et al. 1997. Am. J. Physiol. 273, C37.
      Grierson, J.P., et al. 1992. J. Neurophysiol. 67, 704.
      Lopez, M., et al. 1989. Cytometry 10, 165.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Fluorescent Calcium Probes Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-July-2016 JSW
      Synonyms1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Pentaacetoxymethyl Ester
      DescriptionCell-permeable ester derivative of INDO 1 (Cat. No. 402095). After crossing the cell membrane, INDO 1/AM is rapidly hydrolyzed by cytoplasmic esterases and remains trapped within the cell. Spectral properties in the presence of low calcium concentrations (ex. 349 nm, em. 485 nm) differ from those during high calcium conditions (ex. 330 nm, em. 398 nm). Note: 1 set = 10 x 100 µg.
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number112926-02-0
      Chemical formulaC₄₇H₅₁N₃O₂₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml). PLURONIC® F-127 (Cat. No. 540025) can be used to aid in the dispersion and solubilization.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesZhou, Z., et al. 1998. J. Physiol. 507, 379.
      Griffiths, E.J., et al. 1997. Am. J. Physiol. 273, C37.
      Grierson, J.P., et al. 1992. J. Neurophysiol. 67, 704.
      Lopez, M., et al. 1989. Cytometry 10, 165.