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GF423 HumanKine® IL-2, Human Recombinant Xeno-Free

HumanKine® IL-2, Human Recombinant Xeno-Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P60568
GF423
10 µg  
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      Overview

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      Bulk Size Quantities of HumanKine Growth Factors are Available.
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      Key Spec Table

      SourcePurity
      HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
      Description
      Catalogue NumberGF423
      Trade Name
      • HumanKine®
      DescriptionHumanKine® IL-2, Human Recombinant Xeno-Free
      Alternate Names
      • Interleukin-2
      • IL2
      Background InformationInterleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulated T-cell-dependent immune reactions and control regulatory T cells or Tregs. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. IL-2 also may intensify Th1-mediated diseases, including autoimmune arthritis and may also be interesting clinical targets for those diseases. IL-2 has also been implicated as a possible therapy for infection and cancer. Anti-tumor therapies that include a combination of recombinant IL-2 and recombinant interferon alpha have been promising in clinical studies.
      Product Information
      Formulation
      PresentationProduct is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ300
      Biological Information
      PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
      SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
      UniProt Number
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell
      line). ED50 is typically 0.2-2 ng/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
      Packaging Information
      Material Size10 µg
      Global Trade Item Number
      Catalogue Number GTIN
      GF423 04053252905902