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EZHFGF23-32BK Human FGF-23 Space Saver (Bulk) ELISA Kit

This Human FGF-23 ELISA Kit is used to measure & quantify FGF-23 levels in Metabolism & Inflammation & Immunology research.

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EZHFGF23-32BK
96-well plate  
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      Overview

      Replacement Information
      Description
      Catalogue NumberEZHFGF23-32BK
      DescriptionHuman FGF-23 Space Saver (Bulk) ELISA Kit
      Background InformationStudies demonstrate that Fibroblast Growth Hormone-23 plays a critical role as a phosphate-regulating hormone. FGF-23 is responsible for the inhibition of renal tubular reabsorption of inorganic phosphorus and, consequently, the regulation of phosphorus homeostasis. FGF-23 mRNA is expressed in the brain, in the thymus at low levels, in dendritic cells, with the highest expression in osteocytes and osteoblasts during phases of active bone remodeling. Because circulating levels of FGF-23 are regulated by vitamin D and phosphorus, normal skeletal and soft tissue development require vitamin D and a functional vitamin D signaling pathway. Diseases resulting from aberrant FGF-23 expression include inherited forms of rickets, certain kidney diseases and phosphorus-related tumors.
      References
      Product Information
      Detection methodColorimetric Fluorescent
      Precision, %
      • Intra-assay: < 11%
      • Inter-assay: < 11%
      Quality LevelMQ200
      Applications
      ApplicationThis Human FGF-23 ELISA Kit is used to measure & quantify FGF-23 levels in Metabolism & Inflammation & Immunology research.
      Key Applications
      • ELISA
      Application Notes50µl sample size, 2-Step assay with <4hr incubation time.
      Biological Information
      SpecificityThe antibody pair used in this assay cross-reacts 0.01% to Human FGF- 21 and 0.01% to FGF-19.

      No significant cross-reactivity has been observed to other human and rat molecules/hormones tested
      Species Reactivity
      • Human
      Analytes Available
      • FGF-23
      Accuracy
      • Spike/Recovery: 76-101%
      Physicochemical Information
      Sensitivity
      • Sensitivity in Tissue Culture/Serum/Plasma*:
        9.9 pg/ml

        *Minimum Detectable Concentrations
      Linearity of DilutionPlease contact Technical Service for this information
      Standard Curve Range
      • 9.9 – 2400 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      EZHFGF23-32BK 04053252436949

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