Millipore Sigma Vibrant Logo

374000 Helenalin, A. chamissonis ssp. foliosa

Overview

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
374000-500UG
Fulfillment and Delivery Delayed
Fulfillment and Delivery Delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Glass bottle 500 μg
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewA cell-permeable anti-inflammatory sesquiterpene lactone that acts as a specific NF-κB-DNA binding inhibitor by irreversibly alkylating free sulfhydryls of the cysteine residues on the p65 subunit. Exhibits no effect against the DNA-binding activity of the homodimer of p50 subunit, nor does it affect cellular NF-κB activation/nuclear translocation or IκB dissociation/degradation. An excellent research tool for studying NF-κB-mediated biological processes both in cultures in vitro and in animals in vivo.
      Catalogue Number374000
      Brand Family Calbiochem®
      References
      ReferencesBoulanger, D., et al. 2007. Vet. Microbiol. 119, 330.
      Auld, C.A., et al. 2006. Biochem. Biophys. Res. Commun. 346, 314.
      Huang, P.R., et al. 2005. Cancer Lett. 227, 169.
      Lyss, G., et al. 1998. J. Biol. Chem. 273, 33508.
      Lyss, G., et al. 1997. Biol. Chem. 378, 951.
      Product Information
      CAS number6754-13-8
      FormWhite to off-white solid
      Hill FormulaC₁₅H₁₈O₄
      Chemical formulaC₁₅H₁₈O₄
      Quality LevelMQ100
      Biological Information
      Purity≥95% by HPLC
      Safety Information according to GHS
      RTECSBD9630000
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Toxic
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      374000-500UG 04055977191158