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14-605 Fer Protein, active, 10 µg

14-605
10 µg  
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      Overview

      Replacement Information
      Description
      Catalogue Number14-605
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionFer Protein, active, 10 µg
      OverviewN-terminal His6 tagged, recombinant human Fer amino acids 541-end
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal His6 tagged, recombinant human Fer amino acids 541-end, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
      Entrez Gene Number
      Entrez Gene SummaryFer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
      Gene Symbol
      • FER
      • p94-FER
      • TYK3
      Protein TargetFer
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P16591 # Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control.
      SIZE: 822 amino acids; 94638 Da
      SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Associated with the chromatin.
      TISSUE SPECIFICITY: Expressed in a variety of lymphoid cell lines.
      SIMILARITY: SwissProt: P16591 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. & Contains 1 FCH domain. & Contains 1 protein kinase domain. & Contains 1 SH2 domain.
      Molecular Weight35.6kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of IGF-IRtide (Catalog #12-527)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-605 04053252272622