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324903 Epiregulin, Human, Recombinant

Epiregulin, Human, Recombinant, consists of amino acids 63-108 and expressed in E. coli with an N-terminal methionine.

Epiregulin, Human, Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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324903
  
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥97% by SDS-PAGE
      Description
      OverviewRecombinant, human epiregulin consisting of amino acids 63-108 and expressed in E. coli with an N-terminal methionine. Epiregulin, expressed primarily in the placenta and macrophages, stimulates fibroblast, smooth muscle cell, and hepatocyte proliferation.
      Catalogue Number324903
      Brand Family Calbiochem®
      References
      ReferencesMishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol. 283, F1151.
      Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
      Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
      Das, S.K., et al. 1997. Dev. Biol. 190, 178.
      Komurasaki, T., et al. 1997. Oncogene 15, 2841.
      Toyoda, H., et al. 1997. Biochem. J. 326, 69.
      Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
      Product Information
      FormSolid
      FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.125-0.75 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      324903 0

      Documentation

      Epiregulin, Human, Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      Epiregulin, Human, Recombinant Certificates of Analysis

      TitleLot Number
      324903

      References

      Reference overview
      Mishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol. 283, F1151.
      Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
      Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
      Das, S.K., et al. 1997. Dev. Biol. 190, 178.
      Komurasaki, T., et al. 1997. Oncogene 15, 2841.
      Toyoda, H., et al. 1997. Biochem. J. 326, 69.
      Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-Sepmtember-2011 RFH
      DescriptionRecombinant, human epiregulin consisting of amino acids 63-108 and expressed in E. coli with an N-terminal methionine. Epiregulin, expressed primarily in the placenta and macrophages, stimulates fibroblast, smooth muscle cell, and hepatocyte proliferation.
      FormSolid
      FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
      Purity≥97% by SDS-PAGE
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Biological activityED₅₀ = 0.125-0.75 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
      SolubilityReconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesMishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol. 283, F1151.
      Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
      Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
      Das, S.K., et al. 1997. Dev. Biol. 190, 178.
      Komurasaki, T., et al. 1997. Oncogene 15, 2841.
      Toyoda, H., et al. 1997. Biochem. J. 326, 69.
      Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.