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239900 Cypermethrin - CAS 52315-07-8 - Calbiochem

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Cypermethrin - CAS 52315-07-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Primary Target: calcineurin
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239900
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
52315-07-8C₂₂H₁₉Cl₂NO₃

Pricing & Availability

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239900-10MG
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      Description
      OverviewSynthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
      Catalogue Number239900
      Brand Family Calbiochem®
      Synonyms(R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
      References
      ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
      Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
      Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
      Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
      Product Information
      CAS number52315-07-8
      ATP CompetitiveN
      FormOil
      Hill FormulaC₂₂H₁₉Cl₂NO₃
      Chemical formulaC₂₂H₁₉Cl₂NO₃
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcalcineurin
      Primary Target IC<sub>50</sub>40 pM against calcineurin (protein phosphatase 2B
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSGZ1250000
      Safety Information
      R PhraseR: 25-36/38

      Toxic if swallowed.
      Irritating to eyes and skin.
      S PhraseS: 26-36/37/39-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      239900-10MG 04055977199055

      Documentation

      Cypermethrin - CAS 52315-07-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Cypermethrin - CAS 52315-07-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      239900

      References

      Reference overview
      Richter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
      Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
      Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
      Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.

      Brochure

      Title
      Protein Phosphatases Technical Bulletin

      Citations

      Title
    • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision29-February-2008 JSW
      Synonyms(R,S)-α-Cyano-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
      DescriptionType II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 40 pM). May also have varied effects on ion channels.
      FormOil
      CAS number52315-07-8
      RTECSGZ1250000
      Chemical formulaC₂₂H₁₉Cl₂NO₃
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (15 mg/ml) or Ethanol (5 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Toxic
      Merck USA index14, 2767
      ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
      Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
      Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
      Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
      Citation
    • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
      		•