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230790 Chymostatin - CAS 9076-44-2 - Calbiochem

Chymostatin, CAS 9076-44-2, is chymostatin “A” that specifically inhibits chymotrypsin (ID50 = 150 ng/ml), papain (ID50 = 7.5 µg/ml), and most cysteine proteases.

Chymostatin - CAS 9076-44-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-α-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A = Leu; B = Val; or C = Ile]-phenylalaninal

Primary Target: chymotrypsin
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
9076-44-2C₂₅H₃₀N₆O₅X (X varies from lot to lot)

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      230790-25MG
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          230790-5MG
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              Description
              OverviewContains chymostatin "A" as a major form. Protease inhibitor produced by actinomycetes. Specifically inhibits chymotrypsin (ID50 = 150 ng/ml), papain (ID50 = 7.5 µg/ml), and most cysteine proteases.
              M.W. 604 (avg.).
              Catalogue Number230790
              Brand Family Calbiochem®
              Synonyms[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-α-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A = Leu; B = Val; or C = Ile]-phenylalaninal
              References
              ReferencesMurakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
              Umezawa, H. 1976. Methods Enzymol. 45, 678.
              Product Information
              CAS number9076-44-2
              ATP CompetitiveN
              FormWhite to slightly yellow solid or powder
              Hill FormulaC₂₅H₃₀N₆O₅X (X varies from lot to lot)
              Chemical formulaC₂₅H₃₀N₆O₅X (X varies from lot to lot)
              ReversibleN
              Quality LevelMQ100
              Applications
              ApplicationChymostatin, CAS 9076-44-2, is chymostatin “A” that specifically inhibits chymotrypsin (ID50 = 150 ng/ml), papain (ID50 = 7.5 µg/ml), and most cysteine proteases.
              Biological Information
              Primary Targetchymotrypsin
              Primary Target IC<sub>50</sub>ID50 = 150 ng/ml, 7.5 µg/ml, against chymotrypsin, papain, respectively
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSGC3047700
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage +2°C to +8°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              Catalogue Number GTIN
              230790-10MG 04055977218268
              230790-25MG 04055977218275
              230790-5MG 04055977218282

              Documentation

              Chymostatin - CAS 9076-44-2 - Calbiochem SDS

              Title

              Safety Data Sheet (SDS) 

              Chymostatin - CAS 9076-44-2 - Calbiochem Certificates of Analysis

              TitleLot Number
              230790

              References

              Reference overview
              Murakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
              Umezawa, H. 1976. Methods Enzymol. 45, 678.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision09-April-2018 JSW
              Synonyms[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-α-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A = Leu; B = Val; or C = Ile]-phenylalaninal
              DescriptionMajor form is A. Protease inhibitor produced by actinomycetes. Specifically inhibits chymotrypsin, papain, and most cysteine proteases. Effective at concentrations = 10-100 µM.
              FormWhite to slightly yellow solid or powder
              CAS number9076-44-2
              RTECSGC3047700
              Chemical formulaC₂₅H₃₀N₆O₅X (X varies from lot to lot)
              SolubilityDMSO (20 mg/ml), 5% glacial acetic acid (10 mg/ml)
              Storage +2°C to +8°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Toxicity Standard Handling
              ReferencesMurakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
              Umezawa, H. 1976. Methods Enzymol. 45, 678.