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227036 Cholera Toxin, Vibrio cholerae, Type Inaba 569B, Azide Free - CAS 9012-63-9 - Calbiochem

Overview

Key Spec Table

CAS #
9012-63-9

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227036-1MG
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      Glass bottle 1 mg
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      Description
      OverviewUseful for studies involving adenylate cyclase, AMP, and related membrane-transport phenomena. Consists of a single A subunit surrounded by five polypeptide chains of the B subunits. The A subunit catalyzes the ADP-ribosylation of the α-subunit of G-proteins, reducing intrinsic GTPase activity and activating the α-subunit. The B subunits are responsible for the attachment of the native toxin on the cell surface.
      Useful for tissue culture applications.
      Catalogue Number227036
      Brand Family Calbiochem®
      References
      ReferencesGilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
      Product Information
      CAS number9012-63-9
      ActivityBinding activity is assessed by hemagglutination assay using trisialoganglioside fixed sheep red blood cells.
      ATP CompetitiveN
      DeclarationNot available for sale outside of the United States.
      FormSolid
      FormulationLyophilized from 200 mM NaCl, 50 mM Tris, 1 mM EDTA, pH 7.5.
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary Targetα-subunit of G-proteins
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSLF3100000
      Safety Information
      R PhraseR: 21/22-36/37/38

      Harmful in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 7-36/37

      Keep container tightly closed.
      Wear suitable protective clothing and gloves.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Yes
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C under sterile conditions.
      End use certificateY
      Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
      Global Trade Item Number
      Catalogue Number GTIN
      227036-1MG 04055977200560