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23-055 Cardiac Troponin I, 10 µg

Full length, recombinant human Cardiac Troponin I. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.

Cardiac Troponin I, 10 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Enzyme Assays
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23-055
10 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Key ApplicationsSpeciesCascade Component
      Enzyme AssaysHuman Substrate
      Description
      Catalogue Number23-055
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCardiac Troponin I, 10 µg
      Alternate Names
      • Troponin I
      • cardiac muscle
      • TNNI3
      • TNNC1
      Background InformationTroponin is a complex of three regulatory proteins (Troponin I, Troponin T and Troponin C). It is located on the actin filament and is essential for the calcium-mediated regulation of skeletal and cardiac muscle contraction. There are tissue-specific isoforms of Troponin I, T and C and two subtypes (Cardiac Troponin I and T) are released when the heart muscle has been damaged, such as during a heart attack. The more damage there is to the heart, the greater the amount of Troponin I and T there will be in the blood and currently, Cardiac Troponin I and T are used as the preferred biochemical markers for the diagnosis of myocardial infarction. It has also been demonstrated that Cardiac Troponin I is targeted for degradation by MuRF1, an E3 ubiquitin ligase that has been linked to muscle atrophy
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationFull length, recombinant human Cardiac Troponin I. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
      Key Applications
      • Enzyme Assays
      Biological Information
      Cascade ComponentSubstrate
      Entrez Gene Number
      Purification MethodPurified using immobilized metal affinity chromatography.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      23-055 04053252444074

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      23-055M Cardiac Troponin I, 250 µg Show Pricing & Availability

      Product Families

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      Millipore has removed the complexity of Ubiquitination by providing functionally validated enzymes and substrates, making the pathway readily accessible for research and drug discovery.
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      Categories

      Life Science Research > Drug Discovery and Development > Ubiquitin and Proteasome Screening > Ubiquitination Substrates
      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Ubiquitination Substrates