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05-23-0300 Atrial Natriuretic Factor 1-28, Human - CAS 91917-63-4 - Calbiochem

Atrial Natriuretic Factor 1-28, CAS 91917-63-4, increases the rate of renal excretion. Higher levels are reported in congestive heart failure. Involved in diuresis and blood pressure regulation.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: hANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY

Primary Target: Increases the rate of renal excretion
05-23-0300
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Overview

Key Spec Table

CAS #Empirical Formula
91917-63-4C₁₂₇H₂₀₃N₄₅O₃₉S₃

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      05-23-0300-1MG
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          Description
          OverviewIncreases the rate of renal excretion. Higher levels are reported in congestive heart failure. Inhibits MAP kinase through the natriuretic peptide clearance receptor.
          Catalogue Number05-23-0300
          Brand Family Calbiochem®
          SynonymshANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY
          References
          ReferencesPrins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
          Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.
          Product Information
          CAS number91917-63-4
          ATP CompetitiveN
          FormWhite to off-white lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
          Chemical formulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
          Hygroscopic Hygroscopic
          ReversibleN
          Sold on the basis of peptide contentY
          Quality LevelMQ100
          Biological Information
          Primary TargetIncreases the rate of renal excretion
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Global Trade Item Number
          Catalogue Number GTIN
          05-23-0300-0.5MG 04055977206944
          05-23-0300-1MG 04055977206951