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178456 Apolipoprotein B, Human Plasma, Low-Density Lipoprotein

Native apolipoprotein B from human plasma. It is a dominant protein constituent of LDL and VLDL. Acts as a ligand for LDL receptor, directing clearance of LDL from plasma to the liver.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Apo B, Apo B-100

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178456
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Overview

Replacement Information

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178456-500UG
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      		 Plastic ampoule 500 μg
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      Description
      OverviewNative apolipoprotein B from human plasma. Produced by the liver, and is a dominant protein constituent of LDL that is also present in VLDL. Ligand for LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Mean serum concentration: 950 µg/ml. Higher levels are reported in familial hyperlipidemia, obesity, and diabetes.
      Catalogue Number178456
      Brand Family Calbiochem®
      SynonymsApo B, Apo B-100
      References
      ReferencesJiang, X.C., et al. 2001. Nat. Med. 1, 847.
      Zhou, M., et al. 1995. J. Biol. Chem. 270, 25220.
      Sivaram, P., et al. 1993. J. Biol. Chem. 269, 9409.
      Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.
      Product Information
      FormSolid
      FormulationLyophilized from 50 mM Na₂CO₃, 50 mM NaCl, 10 mM sodium deoxycholate, pH 10.0.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      178456-500UG 04055977222517

      Documentation

      Apolipoprotein B, Human Plasma, Low-Density Lipoprotein SDS

      Title

      Safety Data Sheet (SDS) 

      Apolipoprotein B, Human Plasma, Low-Density Lipoprotein Certificates of Analysis

      TitleLot Number
      178456

      References

      Reference overview
      Jiang, X.C., et al. 2001. Nat. Med. 1, 847.
      Zhou, M., et al. 1995. J. Biol. Chem. 270, 25220.
      Sivaram, P., et al. 1993. J. Biol. Chem. 269, 9409.
      Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-December-2007 JSW
      SynonymsApo B, Apo B-100
      DescriptionNative apolipoprotein B from human plasma. Native apoplipoprotein B from human plasma. Dominant protein constituent of LDL and also present in VLDL. Ligand for the LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Produced by the liver. Mean serum concentration: 950 µg/ml.
      FormSolid
      FormulationLyophilized from 50 mM Na₂CO₃, 50 mM NaCl, 10 mM sodium deoxycholate, pH 10.0.
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥95% by SDS-PAGE
      SolubilityH₂O or Aqueous Buffers. Please refer to the label for lot-specific reconstitution volume.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesJiang, X.C., et al. 2001. Nat. Med. 1, 847.
      Zhou, M., et al. 1995. J. Biol. Chem. 270, 25220.
      Sivaram, P., et al. 1993. J. Biol. Chem. 269, 9409.
      Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.