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ABE473 Anti-hRNF20 Antibody

This hRNF20 antibody is validated for use in WB for the detection of the hRNF20 protein.

Anti-hRNF20 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: RNF20, BRE1A UniProt Number: Q5VTR2
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ABE473
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE473
      DescriptionAnti-hRNF20 Antibody
      Alternate Names
      • E3 ubiquitin-protein ligase BRE1A
      • BRE1-A
      • hBRE1
      • RING finger protein 20
      • hRNF20
      Background InformationBRE1-A (E3 ubiquitin-protein ligase BRE1A) also known by it's gene name hRNF20, plays a role in histone code and gene regulation as a component of the RNF20/40 E3 ubiquitin-protein ligase complex. That complex mediates monoubiquitination of 'Lys-120' of histone H2B,which is a specific tag for epigenetic transcriptional activation as well as a prerequisite for histone H3 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) methylation.
      References
      Product Information
      FormatAffinity Purified
      Control
      • A431 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis hRNF20 antibody is validated for use in WB for the detection of the hRNF20 protein.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human hRNF20.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • RNF20
      • BRE1A
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~113 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected hRNF20 in 10 µg of A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE473 04053252858239

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      Catalogue Number Description  
      MABE948 Anti-BRE1-A (RNF20) Antibody, clone 8A4.2 Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies