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ABN1014 Anti-UFD1L Antibody

ABN1014
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN1014
      DescriptionAnti-UFD1L Antibody
      Alternate Names
      • UFD1L
      • Ubiquitin fusion degradation protein 1 homolog
      • UB fusion protein 1
      Background InformationUFD1L is an essential component of the ubiquitin dependent proteolytic pathway which degrades ubiquitin fusion proteins. UFD1L is part of the three protein complex of UFD1L, VCP and NPLOC4 that binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the proteasome. The complex also regulates spindle disassembly during mitosis and plays an important role in ectoderm development as well. In the adult UFD1L is widely expressed but highest levels are in heart, skeletal muscle, and pancreas.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-UFD1L Antibody is an antibody against UFD1L for use in Immunohistochemistry and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected UFD1L in human pancreas tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human UFD1L.
      EpitopeUnknown
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Bat, Monkey, Primate, Baboon based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • UFD1L
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~38 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human skeletal muscle tissue lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected UFD1L in 10 µg of human skeletal muscle tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN1014 04055977135251