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MAB11041 Anti-Serotonin receptor 1A Antibody, clone 19A9.2

Anti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Signaling Neuroscience Gene Symbol: HTR1A, 5-HT1A, 5HT1a, ADRB2RL, 5-HT-1A, ADRBRL, G-21 UniProt Number: P19327
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MAB11041
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB11041
      DescriptionAnti-Serotonin receptor 1A Antibody, clone 19A9.2
      Alternate Names
      • 5-hydroxytryptamine (serotonin) receptor 1A
      • 5-hydroxytryptamine receptor 1A
      • guanine nucleotide-binding regulatory protein-coupled receptor
      • Serotonin receptor 1A
      • G protein coupled receptor
      • 5-HT1a receptor
      Background InformationSerotonin receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.
      References
      Product Information
      FormatPurified
      HS Code3002 15 90
      Control
      • Rat brain tissue lysate
      PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 1:400 dilution from a previous lot detected Serotonin receptor 1A in normal human brain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to rat Serotonin receptor 1A.
      Clone19A9.2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgMκ
      Species Reactivity
      • Rat
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryRegulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD].
      Gene Symbol
      • HTR1A
      • 5-HT1A
      • 5HT1a
      • ADRB2RL
      • 5-HT-1A
      • ADRBRL
      • G-21
      UniProt Number
      UniProt SummaryFUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

      SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
      Molecular Weight ~40 kDa observed. The calculated molecular weight is 46 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in rat brain tissue lysate.

      Western Blot Analysis: 0.5 µg/mL of this antibody detected Serotonin receptor 1A on 10 µg of rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB11041 04053252645259

      Documentation

      Anti-Serotonin receptor 1A Antibody, clone 19A9.2 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Serotonin receptor 1A Antibody, clone 19A9.2 Certificates of Analysis

      TitleLot Number
      Anti-Serotonin receptor 1A, clone 19A9.2 - 2424802 2424802
      Anti-Serotonin receptor 1A, clone 19A9.2 - 2446955 2446955
      Anti-Serotonin receptor 1A, -2638890 2638890
      Anti-Serotonin receptor 1A, -2776282 2776282
      Anti-Serotonin receptor 1A, -2825963 2825963
      Anti-Serotonin receptor 1A, clone 19A9.2 - 1951090 1951090
      Anti-Serotonin receptor 1A, clone 19A9.2 - 2053404 2053404
      Anti-Serotonin receptor 1A, clone 19A9.2 - 2194085 2194085
      Anti-Serotonin receptor 1A, clone 19A9.2 - 2299593 2299593
      Anti-Serotonin receptor 1A, clone 19A9.2 - 3289309 3289309
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