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ABT275 Anti-Pro-Decorin Antibody

Anti-Pro-Decorin Antibody is an antibody against Pro-Decorin for use in Immunohistochemistry.

Anti-Pro-Decorin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: DCN, SLRR1B UniProt Number: P07585
ABT275
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MIHCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABT275
      DescriptionAnti-Pro-Decorin Antibody
      Alternate Names
      • Decorin
      • Pro-Decorin
      • Bone proteoglycan II
      • PG-S2
      • PG40
      Background InformationDecorin (UniProt P07585; also known as Bone proteoglycan II, PG40, PG-S2) is encoded by the DCN (also known as DSCD, DSPG2, PGII, PGS2, SLRR1B) gene (Entrez Gene ID 1634) in human. Decorin is a pericellular matrix proteoglycan structurally related to two other small proteoglycans, biglycan and fibromodulin. Decorin and biglycan are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while biglycan contains two chains. Decorin modulates collagen fibril formation as well as the bioactivity of various members of the transforming growth factor-beta (TGFbeta) superfamily. Decorin is initially translated as a preproprotein with an N-terminal signal peptide (aa1-16) and propeptide (aa17-30) sequence. Sequential removal of the signal peptide and the propeptide sequence produces pro- and mature decorin, respectively. (PMID 20026052).
      References
      Product Information
      FormatSerum
      PresentationRabbit polyclonal antibody serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Pro-Decorin Antibody is an antibody against Pro-Decorin for use in Immunohistochemistry.
      Key Applications
      • Immunohistochemistry
      Biological Information
      ImmunogenLPH-conjugated linear peptide corresponding to the signal and propeptide of human Pro-Decorin.
      EpitopeSignal and propeptide
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityReacts with decorin preproprotein (359aa) and prodecorin (347aa), but not any of the mature decorin isoforms lacking the N-terminal signal and propeptide sequence. This polyclonal antiserum is also known by LF-110.
      Species Reactivity
      • Human
      • Mouse
      Species Reactivity NoteHuman, Mouse. Predicted to react with Monkey, Rat, Dog, Cat, Horse, and Bovine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • DCN
      • SLRR1B
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight39.7 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human and mouse skin tissue.

      Immunohistochemistry Analysis: A 1:200 dilution of this antibody detected Pro-Decorin in human and mouse skin tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT275 04055977169249

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies