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16-455 Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate

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16-455
10 blots  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      AWBMHRPMonoclonal Antibody
      Description
      Catalogue Number16-455
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Phosphoserine Antibody, clone 4A4, HRP Conjugate
      Alternate Names
      • 4A4
      • anti-phosphoserine
      • phosphoserine antibody
      • pan-phosphoserine
      Background InformationThe identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotrans-mission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that over 95% of all phosphorylation events occur on serine and threonine residues.
      References
      Product Information
      FormatHRP
      Presentation100 μL of protein G purified mouse IgG1 in PBS containing 0.05% Kathon® and HRP stabilizing compounds. Sufficient for a minimum of 10 immunoblots, if used at the optimum concentration of 1:4000 in 10 mL blocking buffer. Liquid.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Phosphoserine Antibody, clone 4A4, HRP Conjugate is an antibody against Phosphoserine for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPhosphoserine conjugated to KLH.
      Epitopephosphoserine
      Clone4A4
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • All
      Species Reactivity NoteRecognizes proteins containing phosphoserine residues, regardless of origin.
      Antibody TypeMonoclonal Antibody
      Modifications
      • Phosphorylation
      Purification MethodProtein G Purified
      Molecular WeightVaries
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by western blot on RIPA lysates from insulin-treated human HEK293 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at 2-8°C from date of shipment.
      NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size10 blots
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      16-455 04053252589614

      Documentation

      Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate Certificates of Analysis

      TitleLot Number
      Anti-Phosphoserine, clone 4A4, HRP -2739253 2739253
      Anti-Phosphoserine, clone 4A4, HRP Conjugate 2470928
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 2393898 2393898
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 2034724 2034724
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 2198973 2198973
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 2219370 2219370
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 2274011 2274011
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 3211122 3211122
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 3596830 3596830
      Anti-Phosphoserine, clone 4A4, HRP Conjugate - 4042847 4042847