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AB10627 Anti-Omentin Antibody

Anti-Omentin Antibody detects level of Omentin & has been published & validated for use in ELISA & WB.

Anti-Omentin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Lipid Metabolism & Weight Regulation Gene Symbol: ITLN1, hIntL, HL1, INTL, Omentin, HL-1, omentin, ITLN, LFR, intelectin, FLJ20022 UniProt Number: Q8WWA0
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AB10627
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, WBRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB10627
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Omentin Antibody
      Background InformationA calcium-dependent lectin with affinity for furanosides, such as galactofuranosyl in bacterial arabinogalactans. 30kD of apparent molecular weight of Omentin migrate at 40-kD under reducing conditions due to glycosylation. Omentin, a novel visceral fat depot-specific secretory protein, enhance insulin-stimulated glucose transport in subcutaneous as well as omental adipocytes and may therefore be implicated in the pathogenesis of obesity.
      References
      Product Information
      FormatPurified
      PresentationLiquid in PBS, pH7.4. Contains no preservatives.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Omentin Antibody detects level of Omentin & has been published & validated for use in ELISA & WB.
      Key Applications
      • ELISA
      • Western Blotting
      Application NotesWestern blot: 1:2,000-1:5,000 using ECL. Reacted with the ~40kDa Omentin His-tagged protein. Suggested blocking and dilution buffer is PBST with 0.05% Tween-20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature.

      ELISA, direct and indirect: 1:2,000-1:5,000.
      Biological Information
      ImmunogenSynthetic peptide: TVGDRWSSQQGSKADYPEGDG, corresponding to amino acids 95-115 of Human Omentin.
      EpitopeAmino acids 95-115 of Human Omentin.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Omentin in western blotting.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ITLN1
      • hIntL
      • HL1
      • INTL
      • Omentin
      • HL-1
      • omentin
      • ITLN
      • LFR
      • intelectin
      • FLJ20022
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q8WWA0 # May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
      SIZE: 313 amino acids; 34962 Da
      SUBUNIT: Homotrimer; disulfide-linked.
      SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
      TISSUE SPECIFICITY: Specifically expressed in the small intestine. Also found the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid; and to a lesser degree in the uterus, spleen, prostate, lymph node and thymus.
      DEVELOPMENTAL STAGE: Found in fetal small intestine and thymus.
      PTM: N-glycosylated.
      SIMILARITY: SwissProt: Q8WWA0 ## Contains 1 fibrinogen C-terminal domain.
      Molecular Weight30-40 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB10627 04053252476136

      Documentation

      Anti-Omentin Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Omentin Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-HUMAN OMENTIN - 3063424 3063424
      RABBIT ANTI-HUMAN OMENTIN - 3204925 3204925
      RABBIT ANTI-HUMAN OMENTIN - 3237539 3237539
      RABBIT ANTI-HUMAN OMENTIN -2638061 2638061
      RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY 3139181
      RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY 2920357
      RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY - 2204872 2204872
      RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY - 2364197 2364197

      References

      Reference overviewPub Med ID
      Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action
      Yang, Rong-Ze, et al
      Am J Physiol Endocrinol Metab, 290:E1253-61 (2006)  2006

      		16531507 16531507
      Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall
      Tsuji, S, et al
      J Biol Chem, 276:23456-63 (2001)  2001

      		11313366 11313366