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MAB3418B Anti-MAP2 Antibody, clone AP20, Biotin Conjugated

Anti-MAP2 Antibody, clone AP20, Biotin Conjugated is an antibody against MAP2 for use in ICC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: Map2, Mtap2 UniProt Number: Q0IIA8
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MAB3418B
100 µL  
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      Overview

      Replacement Information

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R, B, ChICCMBiotinMonoclonal Antibody
      Description
      Catalogue NumberMAB3418B
      DescriptionAnti-MAP2 Antibody, clone AP20, Biotin Conjugated
      Alternate Names
      • Microtubule-associated protein 2
      • MAP-2
      • MAP2
      Background InformationThe microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.
      References
      Product Information
      FormatBiotin
      Control
      • Rat cortex tissue
      PresentationPurified mouse monoclonal IgG conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.
      Quality LevelMQ100
      Applications
      ApplicationAnti-MAP2 Antibody, clone AP20, Biotin Conjugated is an antibody against MAP2 for use in ICC.
      Key Applications
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: A 1:25 dilution from a representative lot detected MAP2 in rat E18 primary cortex cells.
      Biological Information
      ImmunogenBovine brain microtubule protein
      CloneAP20
      HostMouse
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Bovine
      • Chicken
      Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Chicken, Human, and Mouse based on 100% sequence homology. Predicted to react with Bovine based on immunogen design.
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Map2
      • Mtap2
      Purification MethodProtein G Purified
      UniProt Number
      Molecular WeightThe unconjugated parent antibody (Cat. No. MAB3418) has an observed molecular weight at ~230 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in rat cortex tissue.

      Immunohistochemistry Analysis: A 1:25 dilution of this antibody detected MAP2 in rat cortex tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8 °C in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB3418B 04053252647734

      Documentation

      Anti-MAP2 Antibody, clone AP20, Biotin Conjugated SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-MAP2 Antibody, clone AP20, Biotin Conjugated Certificates of Analysis

      TitleLot Number
      Anti-MAP2, clone AP20, Biotin -2735800 2735800
      Anti-MAP2, clone AP20, Biotin Conjugated 2978910
      Anti-MAP2, clone AP20, Biotin Conjugated - 2391151 2391151
      Anti-MAP2, clone AP20, Biotin Conjugated - 2814734 2814734
      Anti-MAP2, clone AP20, Biotin Conjugated - 3180908 3180908
      Anti-MAP2, clone AP20, Biotin Conjugated - 3470745 3470745
      Anti-MAP2, clone AP20, Biotin Conjugated - 3878842 3878842
      Anti-MAP2, clone AP20, Biotin Conjugated - 4030991 4030991
      Anti-MAP2, clone AP20, Biotin Conjugated - 4215004 4215004
      Anti-MAP2, clone AP20, Biotin Conjugated - 4252108 4252108
      Show more

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies