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ABN266 Anti-KIF5A Antibody

Detect the KIF5A protein using this Anti-KIF5A validated for use in WB & ICC.

Anti-KIF5A Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: KIF5A UniProt Number: Q12840
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ABN266
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN266
      DescriptionAnti-KIF5A Antibody
      Alternate Names
      • Kinesin heavy chain isoform 5
      • neuronal kinesin heavy chain
      • NKHC
      Background InformationKinesin heavy chain isoform 5A (KIF5) is a member of the kinesin-like protein family. These proteins are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5A performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5A was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. Mutations in one of the isoforms of KIF5 (KIF5A) is thought to be involved in hereditary spastic paraplegias.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Mouse brain nuclear extract
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect the KIF5A protein using this Anti-KIF5A validated for use in WB & ICC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: 5 µg/mL from a representative lot detected KIF5A in K562 cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human KIF5A.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody can recognize isoforms KIF5A, KIF5B, and KIF5C.
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • KIF5A
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~117 kDa observed. Uncharacterized bands may appear at ~45 kDa and ~57 kDa in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse brain nuclear extract.

      Western Blot Analysis: 1 µg/mL of this antibody detected KIF5A in 15 µg/mL of mouse brain nuclear extract.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN266 04053252830952

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies