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MABC155 Anti-KIF3A Antibody, clone 4F9.1

This Anti-KIF3A Antibody, clone 4F9.1 is validated for use in Western Blotting and Immunohistochemistry for the detection of KIF3A.

Anti-KIF3A Antibody, clone 4F9.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: KIF3, KIF3A UniProt Number: Q9Y496
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MABC155
100 μg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC155
      DescriptionAnti-KIF3A Antibody, clone 4F9.1
      Alternate Names
      • Microtubule plus end-directed kinesin motor 3A
      • KIF3A
      • Kinesin-like protein KIF3A
      Background InformationKinesin-like protein KIF3A (UniProt Q9Y496; also known as Kinesin family protein 3A, Microtubule plus end-directed kinesin motor 3A) is encoded by the KIF3A (also known as FLA10, KIF3, KLP-20) gene (Gene ID 11127) in human. Kinesin-2 is a heterotrimeric motor protein composed of two kinesin-related subunits, KIF3A and KIF3B, and an associated protein KAP3. The kinesin-2 motor KIF3A/B drives intraflagellar transport (IFT) of tubulins and other axonemal building blocks in cilia and flagella, pigment granules in melanosomes, and vesicles in neurons. Defects in these transport processes are linked to polycystic kidney disease and neurodegenerative diseases.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-KIF3A Antibody, clone 4F9.1 is validated for use in Western Blotting and Immunohistochemistry for the detection of KIF3A.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected KIF3A in 10 µg of rat hippocampus tissue lysate.
      Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected KIF3A in human cerebellum and human cerebral cortex tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminal of human KIF3A.
      Epitope C-terminal
      Clone4F9.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • KIF3
      • KIF3A
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~75 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse cerebellum tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected KIF3A in 10 µg of mouse cerebellum tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC155 04055977181593

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies