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371754 Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb

Anti-Gqα- and G₁₁α-Subunits, Internal (283-300), rabbit polyclonal, recognizes the ~42 kDa Gqα- and the ~43 kDa G₁₁α-subunits. Validated for use in WB and neutralization studies.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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371754
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
H, M, RRbPolyclonal Antibody

Pricing & Availability

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371754-50UL
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      Description
      OverviewRecognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family.
      Catalogue Number371754
      Brand Family Calbiochem®
      References
      ReferencesWange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
      Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
      Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.
      Product Information
      FormLiquid
      FormulationIn 140 mM NaCl, 100 mM potassium phosphate, pH 7.0.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Neutralization Studies
      Application NotesImmunoblotting (1:1000)
      Neutralization Studies (see comments)
      Application CommentsThe antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogena synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      371754-50UL 04055977213355

      Documentation

      Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb Certificates of Analysis

      TitleLot Number
      371754

      References

      Reference overview
      Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
      Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
      Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-August-2007 RFH
      ApplicationImmunoblotting (1:1000)
      Neutralization Studies (see comments)
      DescriptionProtein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunit proteins.
      HostRabbit
      Immunogena synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits
      IsotypeIgG
      Specieshuman, mouse, rat
      FormLiquid
      FormulationIn 140 mM NaCl, 100 mM potassium phosphate, pH 7.0.
      PreservativeNone
      CommentsThe antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesWange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
      Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
      Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.