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ABN428 Anti-Fezf2 Antibody

This Anti-Fezf2 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Fezf2.

Anti-Fezf2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: FEZF2, FEZL, ZNF312 UniProt Number: Q8TBJ5
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ABN428
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN428
      DescriptionAnti-Fezf2 Antibody
      Alternate Names
      • Fez family zinc finger protein 2
      • Forebrain embryonic zinc finger-like protein 2
      • Zinc finger protein 312
      • Zinc finger protein Fez-like
      Background InformationFezf2 is a transcriptional repressor protein. It is required for the specification of corticospinal motor neurons and other subcerebral projection neurons. FeZf2 also plays a role in the layer and subcortical specific patterning of the subcortical projections and axonal fasciculations that develop in the brain. Fezf2 also controls the development of the dendritic arborization and spines of the large layer V pyramidal neurons. Thus biological processes involving Fezf2 include neuronal patterning, differentiation, neurogenesis, axon guidance, fasciculation, cortex development, anterior/posterior patterning, dendrite development, and locomotory behavior, and it was recently identified as a multipotent progenitor marker for neocortical projection neurons, astrocytes, and oligodendrocytes.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Fezf2 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Fezf2.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Fezf2 in rat spinal cord tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the Engrailed homology 1 repressor domain of human Fezf2.
      EpitopeEngrailed homology 1 repressor domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Bovine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FEZF2
      • FEZL
      • ZNF312
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~50 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse E13-14 brain tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Fezf2 in 10 µg of mouse E13-14 brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN428 04053252986475