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MAB3101 Anti-Connexin 45 Antibody, near CT, cytoplasmic, clone 5B9.2

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MAB3101
100 µg  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R, RbICC, WBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB3101
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Connexin 45 Antibody, near CT, cytoplasmic, clone 5B9.2
      Alternate Names
      • Cx45
      Product Information
      FormatPurified
      PresentationLiquid at 1 mg/mL in 0.02M PB with 0.25 M NaCl, pH=7.6 containing 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Connexin 45 Antibody, near C-terminus, cytoplasmic, clone 5B9.2 detects level of Connexin 45 & has been published & validated for use in IC & WB.
      Key Applications
      • Immunocytochemistry
      • Western Blotting
      Application NotesImmunblotting (~46 kDa)

      Immunocytochemistry

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenThe peptide sequence used for the immunogen was H-Gln-Ala-Tyr-Ser-His-Gln-Asn-Asn-Pro-His-Gly-Pro-Arg-Glu-Cys-OH conjugated to KLH, corresponding to amino acids 354-367 of human connexin 45.
      Epitopenear C-terminus, cytoplasmic
      Clone5B9.2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityRecognizes Human Connexin 45.

      SPECIES REACTIVITIES:

      Due to sequence homologies, this antibody is also expected to react with canine (100% homology) and mouse (92% homology) Connexin 45. Also confirmed to work on rat C6 cells. Others not tested.
      IsotypeIgG1
      Species Reactivity
      • Human
      • Rat
      • Rabbit
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • ENSG00000182963
      • Cx45
      • Connexin-45
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P36383 # One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      SIZE: 396 amino acids; 45483 Da
      SUBUNIT: A connexon is composed of a hexamer of connexins.
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
      SIMILARITY: SwissProt: P36383 ## Belongs to the connexin family. Alpha-type (group II) subfamily.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 12 months.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Catalogue Number GTIN
      MAB3101 04053252614477