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MAB1476-I Anti-Chymotrypsin (Hu Pancreas) Antibody, clone CHYMO10-104.10

Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10, Cat. No. MAB1476-I, is a mouse monoclonal antibody that detects Trypsin and is tested for use in ELISA and Immunohistochemistry (Paraffin).

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MAB1476-I
100 μg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberMAB1476-I
      DescriptionAnti-Chymotrypsin (Hu Pancreas) Antibody, clone CHYMO10-104.10
      Background InformationChymotrypsin is a serine endopeptidase that is synthesized in the pancreatic acinar cells as chymotrypsinogen that is cleaved by trypsin to generate active chymotrypsin. Activation of chymotrypsinogen involves proteolytic cleavage at two sites. The resultant three chains are held together by five disulfide bonds. Chymotrypsin is reported to preferentially cleave peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a large hydrophobic amino acid (tyrosine, tryptophan, and phenylalanine). The aromatic ring in their sidechain that fits into a 'hydrophobic pocket' (the S1 position) of the enzyme. Two predominant forms of chymotrypsin have been described and are designated as chymotrypsin A and B. They display high degree of homology but have significantly different proteolytic characteristics. The active site residues in chymotrypsin are far apart in the primary sequence but are brought together in a crevice formed between the two protein domains.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody in buffer containing PBS, pH 7.4, containing no preservatives.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10, Cat. No. MAB1476-I, is a mouse monoclonal antibody that detects Trypsin and is tested for use in ELISA and Immunohistochemistry (Paraffin).
      Key Applications
      • ELISA
      • Immunohistochemistry (Paraffin)
      Application NotesELISA: (Dilution is assay dependent)

      Immunohistochemistry: 1:1000.

      Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user
      Biological Information
      ImmunogenPurified human pancreatic chymotrypsin.
      EpitopeUnknown
      CloneCHYMO10-104.10
      ConcentrationPlease refer to guidance on suggested starting dilutions and/or titers per application and sample type.
      HostMouse
      SpecificityClone CHYMO10-104.10 is a mouse monoclonal antibody that detects human Chymotrypsin.
      IsotypeIgG1
      Species Reactivity
      • Human
      Species Reactivity NoteHuman
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CTRL
      • CTRL1
      • chymotrypsin-like
      • MGC70821
      • EC 3.4.21
      Purification MethodProtein G purified
      UniProt Number
      Molecular Weight28.0 kDa calculated.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in convenient aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 L or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB1476-I 04065265651394

      Documentation

      Anti-Chymotrypsin (Hu Pancreas) Antibody, clone CHYMO10-104.10 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Chymotrypsin (Hu Pancreas) Antibody, clone CHYMO10-104.10 Certificates of Analysis

      TitleLot Number
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 3919633 3919633
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4032736 4032736
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4047621 4047621
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4070801 4070801
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4080180 4080180
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4086383 4086383
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4094588 4094588
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4095806 4095806
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4128311 4128311
      Anti-Chymotrypsin (Hu Pancreas), clone CHYMO10-104.10 - 4134657 4134657
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