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MABF1581 Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 Antibody

This armenian hamster monoclonal Anti-CD3e Antibody (Mouse), PE-Cy7, clone 145-2C11, Cat. No. MABF1582 is validated for use in Flow Cytometry, for the detection of CD3e.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Cd3e UniProt Number: P22646
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MABF1581
25 μg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MFCAHmPE-Cy7Monoclonal Antibody
      Description
      Catalogue NumberMABF1581
      DescriptionAnti-CD3e (Mouse), PE-Cy7, clone 145-2C11 Antibody
      Alternate Names
      • T-cell surface glycoprotein CD3 epsilon chain
      • T-cell surface antigen T3/Leu-4 epsilon chain
      • CD3e
      • CD3e
      Background InformationThe 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells. The 145-2C11 antibody is a widely used phenotypic marker for mouse T cells. In addition, binding of 145-2C11 antibody to CD3e can induce cell activation.
      References
      Product Information
      FormatPE-Cy7
      PresentationPurified Armenian Hamster monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
      Quality LevelMQ100
      Applications
      ApplicationThis armenian hamster monoclonal Anti-CD3e Antibody (Mouse), PE-Cy7, clone 145-2C11, Cat. No. MABF1582 is validated for use in Flow Cytometry, for the detection of CD3e.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      Clone145-2C11
      ConcentrationPlease refer to lot specific datasheet.
      HostArmenian Hamster
      IsotypeIgG
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Cd3e
      Purification MethodPurified by size-exclusion chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 1 μg from a representative lot detected CD3e in one million C57Bl/6 splenocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size25 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABF1581 04055977293456

      Documentation

      Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 Antibody Certificates of Analysis

      TitleLot Number
      Anti-CD3e (Mouse), PE-Cy7, -QVP1504287 QVP1504287
      Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 - VP2111118 VP2111118
      Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 - VP2308113 VP2308113

      Brochure

      Title
      New Products Flyer- Vol 4 Signaling Feature- NEW! Phosphohistidine Antibody

      Posters

      Title
      Post-Translational Modifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies