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MAB5580 Anti-Arrestin Antibody, visual

Detect Arrestin using this Anti-Arrestin Antibody, visual validated for use in IH, IP & WB.

Anti-Arrestin Antibody, visual MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Sensory & PNS Gene Symbol: ARR3, Arrestin-C, CAR, ARRX, C-arrestin, cArr UniProt Number: P79260
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MAB5580
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, Gt, H, Po, R, ShIHC, IP, WBMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMAB5580
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Arrestin Antibody, visual
      Alternate Names
      • S-antigen
      • rod arrestin
      Background InformationVisual arrestin is a 48 kDa protein expressed exclusively in retinal photoreceptor cells where it regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual arrestin is the major pathogenetic autoantigen in human autoimmume imflammatory eye disease.
      Product Information
      FormatAscites
      PresentationAscites fluid. Liquid.
      Quality LevelMQ100
      Applications
      ApplicationDetect Arrestin using this Anti-Arrestin Antibody, visual validated for use in IH, IP & WB.
      Key Applications
      • Immunohistochemistry
      • Immunoprecipitation
      • Western Blotting
      Application NotesWestern blot: 48kDa

      Immunohistochemistry

      Immunopurification of arrestin

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenPorcine visual arrestin.
      HostMouse
      SpecificityVisual arrestin. The antibody has not been tested for reactivity to arrestin in other tissues.
      IsotypeIgG1
      Species Reactivity
      • Bovine
      • Goat
      • Human
      • Pig
      • Rat
      • Sheep
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • ARR3
      • Arrestin-C
      • CAR
      • ARRX
      • C-arrestin
      • cArr
      UniProt Number
      UniProt SummaryFunction: Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
      Tissue specificity: Retina and pineal gland. Also expressed in the anterior tissues such as the ciliary epithelium and iris epithelium.
      Involvement in disease: S-antigen induces autoimmune uveitis.
      Miscellaneous: Arrestin binds calcium By similarity.
      Sequence similarities: Belongs to the arrestin family.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Catalogue Number GTIN
      MAB5580 04053252357855