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171615 Anti-β-Amyloid Precursor-Like Protein 1, C-Terminal (643-653) Rabbit pAb

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
171615
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      Overview

      This product has been discontinued.



      Please refer to our complete listings of amyloid precursor protein antibodies and amyloid precursor protein antibodies on millipore.com for possible alternatives.






      Recognizes the APLP1 protein. Does not recognize APP or APLP2.
    • Antibody Target Gene Symbol: APLP1
    • Target Synonym: APLP, Aplp1 retired, RGD1561211
    • Entrez Gene Name: amyloid beta (A4) precursor-like protein 1
    • Hu Entrez ID: 333
    • Mu Entrez ID: 11803
    • Rat Entrez ID: 502317
      		•
      Catalogue Number171615
      Brand Family Calbiochem®
      References
      ReferencesWalsh D.M., et al. 2002. Biochemistry in press.
      Thinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
      von Koch, C.S., et al. 1997. Neurobiol. Aging 18, 661.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Immunofluorescence
      Immunoprecipitation
      Application NotesImmunoblotting (1:5000-1:20,000)
      Immunofluorescence (1:250-1:500)
      Immunoprecipitation (1-2 µl/mg cell or tissue lysate)
      Application CommentsDoes not react with APP and APLP2. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogena synthetic peptide [(C)NPTYRFLEERP] corresponding to amino acids 643-653 of mouse APLP1, conjugated to KLH
      ImmunogenMouse
      HostRabbit
      IsotypeIgG
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      171615 0

      Documentation

      Anti-β-Amyloid Precursor-Like Protein 1, C-Terminal (643-653) Rabbit pAb Certificates of Analysis

      TitleLot Number
      171615

      References

      Reference overview
      Walsh D.M., et al. 2002. Biochemistry in press.
      Thinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
      von Koch, C.S., et al. 1997. Neurobiol. Aging 18, 661.

      Brochure

      Title
      Alzheimer's Disease Brochure & Technical Guide

      Citations

      Title
    • Meir H. Scheinfeld, et al. (2002) Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription. Journal of Biological Chemistry 277, 44195-44201.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-June-2007 RFH
      ApplicationImmunoblotting (1:5000-1:20,000)
      Immunofluorescence (1:250-1:500)
      Immunoprecipitation (1-2 µl/mg cell or tissue lysate)
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the APLP1 protein.
      BackgroundAmyloid precursor-like protein 1 (APLP1) is a member of a family of related polypeptides that includes amyloid precursor proteins (APP) and amyloid precursor-like protein 2 (APLP2). APP generates β-amyloid peptide, deposits of which form the amyloid plaques that characterize Alzheimer's disease.
      HostRabbit
      Immunogen speciesMouse
      Immunogena synthetic peptide [(C)NPTYRFLEERP] corresponding to amino acids 643-653 of mouse APLP1, conjugated to KLH
      IsotypeIgG
      Specieshuman, mouse, rat
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsDoes not react with APP and APLP2. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesWalsh D.M., et al. 2002. Biochemistry in press.
      Thinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
      von Koch, C.S., et al. 1997. Neurobiol. Aging 18, 661.
      Citation
    • Meir H. Scheinfeld, et al. (2002) Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription. Journal of Biological Chemistry 277, 44195-44201.
      		•