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ABN479 Anti-ATP2C1 Antibody

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ABN479
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN479
      DescriptionAnti-ATP2C1 Antibody
      Alternate Names
      • Calcium-transporting ATPase type 2C member 1
      • ATPase 2C1
      • ATP-dependent Ca(2+) pump PMR1
      • ATP2C1
      Background InformationCalcium-transporting ATPase type 2C member 1 (ATP2C1) is a member of the cation transport ATPase (P-type) (TC 3.A.3) family. ATP2C1 catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. It may also play an important role as a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. It is found in most tissues except colon, thymus, spleen and leukocytes.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Mouse brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-ATP2C1 Antibody is a highly specific rabbit polyclonal antibody, that targets Calcium-transporting ATPase type 2C member 1 & has been tested in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected ATP2C1 in mouse brain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human ATP2C1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody can recognize the three longest isoforms at ~101 kDa, ~103 kDa, and ~105 kDa.
      Species Reactivity
      • Mouse
      Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • ATP2C1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~180 kDa observed. Uniprot describes 6 isoforms ranging between ~97 kDa and ~105 kDa. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.

      Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected ATP2C1 in 15 µg of mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN479 04053252905513