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MAB312-AF647 Anti-A2B5 Antibody, clone A2B5-105 Antibody, Alexa Fluor® 647 Conjugate

Anti-A2B5 Antibody, clone A2B5-105, Alexa Fluor® 647 Conjugate Cat. No. MAB312-AF647, is a highly specific mouse monoclonal antibody that targets A2B5 and has been tested in Immunocytochemistry and Flow Cytometry.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience UniProt Number: Not Applicable
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MAB312-AF647
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MaFC, ICCMAlexaFluor®647Monoclonal Antibody
      Description
      Catalogue NumberMAB312-AF647
      DescriptionAnti-A2B5 Antibody, clone A2B5-105 Antibody, Alexa Fluor® 647 Conjugate
      Alternate Names
      • F12A2B5
      • 105
      Background InformationA2B5 (also known as F12A2B5) is a cell surface ganglioside expressed on developing thymic epithelial cells, oligodendrocyte progenitors, and neuroendocrine cells. It is highly expressed in embryonic and neonatal tissue, but in the adult mammalian brain its expression is restricted mainly to areas that retain neurogenic potential, such as the subventricular zone (SVZ). Hence, A2B5 is considered as a marker for immature glial-committed precursors, which are permanently generated in the SVZ. Its expression is also considered as a marker for various cancers, including astrocytoma, glioma, pancreatic islet tumors, and squamous cell carcinoma. Explants from A2B5+ tumor cells display a typical progenitor morphology and clearly indicate their immature state. Tumors expressing A2B5 antigen exhibit higher rates of recurrence.
      References
      Product Information
      FormatAlexaFluor®647
      PresentationPurified mouse IgM Alexa Fluor® 647 conjugate in PBS with 1.5% BSA and 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-A2B5 Antibody, clone A2B5-105, Alexa Fluor® 647 Conjugate Cat. No. MAB312-AF647, is a highly specific mouse monoclonal antibody that targets A2B5 and has been tested in Immunocytochemistry and Flow Cytometry.
      Key Applications
      • Flow Cytometry
      • Immunocytochemistry
      Application NotesFlow Cytometry Analysis: 1:400 dilution from a representative lot immunostained the surface of PC12 cells.

      The unconjugated antibody (Cat. No. MAB312) is also available for flow cytometry, immunocytochemistry, immunofluorescence, and immunohistochemistry applications.
      Biological Information
      ImmunogenEmbryonic chicken retinal cells.
      CloneA2B5-105
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityThis monoclonal antibody detects A2B5 in mammalian cells.
      IsotypeIgM
      Species Reactivity
      • Mammals
      Species Reactivity NoteMammals.
      Antibody TypeMonoclonal Antibody
      Purification MethodAmmonium sulfate.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by immunocytochemistry of PC12 cells.

      Immunocytochemistry Analysis: A 1:100 Dilution of this antibody immunostained the surface of PC12 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB312-AF647 04054839134364