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171375 Amphotericin B, Streptomyces sp. - CAS 1397-89-3 - Calbiochem

A polyene antifungal antibiotic that non-specifically induces loss of low molecular weight substances from cells. Binds to sterols and disrupts osmotic integrity of fungal membrane. Causes suppression

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MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Fungizone

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      Overview

      Key Spec Table

      CAS #Empirical Formula
      1397-89-3C₄₇H₇₃NO₁₇
      Description
      OverviewA polyene antifungal antibiotic that non-specifically induces loss of low molecular weight substances from cells. Binds to sterols and disrupts osmotic integrity of fungal membrane. Causes suppression of bone marrow progenitor cells.
      Catalogue Number171375
      Brand Family Calbiochem®
      SynonymsFungizone
      References
      ReferencesTollemar, J., et al. 1995. Transplantation 59, 45.
      Charak, B.S., et al. 1994. Br. J. Haematol. 88, 693.
      Barth, C., et al. 1993. J. Biophys. 64, 92.
      Product Information
      CAS number1397-89-3
      FormYellow solid
      Hill FormulaC₄₇H₇₃NO₁₇
      Chemical formulaC₄₇H₇₃NO₁₇
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity>86% by HPLC
      Safety Information according to GHS
      RTECSBU2625000
      Safety Information
      R PhraseR: 20/21-36/37/38

      Harmful by inhalation and in contact with skin.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Solutions in tissue culture media are stable for 3 days at 37°C.
      Global Trade Item Number
      Catalogue Number GTIN
      171375 0