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110175 Acetyl-Pepstatin - CAS 28575-34-0 - Calbiochem

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
28575-34-0C₃₁H₅₇N₅O₉

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110175-1MG
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      Description
      OverviewAn aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (Ki = 20 nM at pH 4.7) and HIV-2 proteinase (Ki = 5 nM at pH 4.7). Acts as a substrate-analog inhibitor.
      Catalogue Number110175
      Brand Family Calbiochem®
      SynonymsAc-Val-Val-(3S,4S)-Sta-Ala-(3S,4S)-Sta-OH
      References
      ReferencesUlrich, B., et al. 2000. Protein Sci. 9, 2232.
      Song, K., et al. 1992. Kidney Int. 42, 639.
      Richards, A.D., et al. 1989. FEBS Lett. 247, 113.
      Richards, A.D., et al. 1989. FEBS Lett. 253, 214.
      Product Information
      CAS number28575-34-0
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₃₁H₅₇N₅O₉
      Chemical formulaC₃₁H₅₇N₅O₉
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetHIV-1 proteinase
      Primary Target K<sub>i</sub>20 nM at pH 4.7 against HIV-1 proteinase
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      110175-1MG 04055977208016

      Documentation

      Acetyl-Pepstatin - CAS 28575-34-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      110175

      References

      Reference overview
      Ulrich, B., et al. 2000. Protein Sci. 9, 2232.
      Song, K., et al. 1992. Kidney Int. 42, 639.
      Richards, A.D., et al. 1989. FEBS Lett. 247, 113.
      Richards, A.D., et al. 1989. FEBS Lett. 253, 214.

      User Guides

      Title
      Color Card 109175 pH-Indicator solution Universal Indikator / pH-Indikatorlösung Universalindikator pH 0-5 (Don't use printout for evaluation)
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-April-2008 RFH
      SynonymsAc-Val-Val-(3S,4S)-Sta-Ala-(3S,4S)-Sta-OH
      DescriptionAn aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (Ki = 20 nM at pH 4.7) and HIV-2 proteinase (Ki = 5 nM at pH 4.7).
      FormWhite solid
      CAS number28575-34-0
      Chemical formulaC₃₁H₅₇N₅O₉
      Purity≥97% by HPLC
      Solubility50% Acetic acid (5 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesUlrich, B., et al. 2000. Protein Sci. 9, 2232.
      Song, K., et al. 1992. Kidney Int. 42, 639.
      Richards, A.D., et al. 1989. FEBS Lett. 247, 113.
      Richards, A.D., et al. 1989. FEBS Lett. 253, 214.