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480354 7S NGF, Mouse Submaxillary Glands

7S NGF, Mouse Submaxillary Glands MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 7S Nerve Growth Factor

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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      Native 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits: (α: β: γ): 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
      Catalogue Number480354
      Brand Family Calbiochem®
      Synonyms7S Nerve Growth Factor
      References
      ReferencesBax, B., et al. 1997. Structure 5, 1275.
      Shao, N., et al. 1993. Brain Res. 609, 338.
      Varon, S., et al. 1972. Methods Neurochem. 3, 203.
      Product Information
      FormLyophilized
      FormulationLyophilized from sterile H₂O.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀: Determined by half maximal growth of PC12 cells. Please see vial label for lot-specific ED₅₀.
      Physicochemical Information
      ContaminantsEGF: none detected
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 weeks at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      480354 0

      Documentation

      7S NGF, Mouse Submaxillary Glands Certificates of Analysis

      TitleLot Number
      480354

      References

      Reference overview
      Bax, B., et al. 1997. Structure 5, 1275.
      Shao, N., et al. 1993. Brain Res. 609, 338.
      Varon, S., et al. 1972. Methods Neurochem. 3, 203.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-January-2010 JSW
      Synonyms7S Nerve Growth Factor
      DescriptionNative 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits (α:β:γ) 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
      FormLyophilized
      FormulationLyophilized from sterile H₂O.
      ContaminantsEGF: none detected
      Biological activityED₅₀: Determined by half maximal growth of PC12 cells. Please see vial label for lot-specific ED₅₀.
      SolubilityNeutral (pH 7.0) buffers (1 mg/ml). The 7S NGF complex will dissociate in acidic or basic buffers, so it is critical that the pH of the reconstitution buffer be neutral.
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 weeks at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 6477
      ReferencesBax, B., et al. 1997. Structure 5, 1275.
      Shao, N., et al. 1993. Brain Res. 609, 338.
      Varon, S., et al. 1972. Methods Neurochem. 3, 203.

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      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors