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504841 5,7-Dichlorokynurenic Acid, Sodium Salt - CAS 1184986-70-6 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA

Primary Target: NMDA receptors
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504841
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1184986-70-6C₁₀H₄Cl₂NNaO₃

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      Description
      OverviewA very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79 nM vs. [3H]-glycine).
      Catalogue Number504841
      Brand Family Calbiochem®
      Synonyms5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA
      References
      ReferencesBaron, B., et al. 1991. Eur. J. Pharmacol. 206, 149.
      Baron, B., et al. 1990. Mol. Pharmacol. 38, 554.
      Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res. 18, 91.
      Product Information
      CAS number1184986-70-6
      FormWhite solid
      Hill FormulaC₁₀H₄Cl₂NNaO₃
      Chemical formulaC₁₀H₄Cl₂NNaO₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNMDA receptors
      Primary Target K<sub>i</sub>79 nM
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.04841.0001 04055977243581

      Documentation

      5,7-Dichlorokynurenic Acid, Sodium Salt - CAS 1184986-70-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      5,7-Dichlorokynurenic Acid, Sodium Salt - CAS 1184986-70-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      504841

      References

      Reference overview
      Baron, B., et al. 1991. Eur. J. Pharmacol. 206, 149.
      Baron, B., et al. 1990. Mol. Pharmacol. 38, 554.
      Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res. 18, 91.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-November-2016 JSW
      Synonyms5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA
      DescriptionA very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79 nM vs. [3H]-glycine).
      FormWhite solid
      CAS number1184986-70-6
      Chemical formulaC₁₀H₄Cl₂NNaO₃
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityH₂O (10 mM) or 1N NaOH (100 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBaron, B., et al. 1991. Eur. J. Pharmacol. 206, 149.
      Baron, B., et al. 1990. Mol. Pharmacol. 38, 554.
      Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res. 18, 91.