β-Catenin Antibodies, Kits & Proteins
Recommended Products
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G43-017 Millipore HS Shaft Adapter T60 -
ABS2207-25UL Sigma-Aldrich Anti-Inhibin α chain (INHA) -
NU050/4710-221 Millipore NA½inch V.Body 90° TC connectable 316L Ra<0.5 butt EP -
CBL158 Sigma-Aldrich Anti-Integrin β2 [CD18] Antibody -
655206-50ML Millipore TWEEN® 20, PROTEIN GRADE® Detergent, 10% Solution, Sterile-Filtered - CAS 9005-64-5 - Calbiochem -
MABS2191-25UG Sigma-Aldrich Anti-Cytochrome b-245/p22phox Antibody, clone CS9 -
1282111001 SAFC Sodium sulfate -
PMIX0100L2264375 Millipore Mobius®, Silver, 100L PF PWR Mixer Bag A
Overview
β-catenin is the first characterized member of the β -catenin family. β-catenin contains 12 ARM repeats and has a dual function, depending on its localization. Cytoplasmic β-catenin is a critical component of E-cadherin/catenin adhesion complexes and regulates cadherin-dependent cell-cell interactions.When localized to the nucleus, β -catenin regulates binding to transcription factors from the TCF/LEF family, activating transcription. β -catenin is expressed in hair follicle cells such as those found in the inner and outer portions of the root sheaths, and the basal and peripheral matrix cells. Expression has also been observed in colon tissue. Defects in expression have been linked to the development of several tumors and cancers.