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679100 Vitamin D₂, 1α-Hydroxy- - CAS 54573-75-0 - Calbiochem

A vitamin D2 analog with potential for the treatment of secondary hyperparathyroidism and metabolic bone disease.

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Synonyme: 1α-OH-D₂

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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      54573-75-0C₂₈H₄₄O₂
      Description
      OverviewA vitamin D2 analog with potential for the treatment of secondary hyperparathyroidism and metabolic bone disease. May be an effective and safer alternative to Calcitriol (1α,25-Dihydroxyvitamin D3; Cat. No. 679101) for suppressing PTH without causing hypercalcemia. Metabolized in vivo to the natural active dihydroxylated metabolite of vitamin D2, 1α,25-dihydroxyvitamin D2.
      Catalogue Number679100
      Brand Family Calbiochem®
      Synonyms1α-OH-D₂
      References
      ReferencesCoburn, J.W., et al. 1996. Nephrol. Dial. Transplant. 11 (Suppl. 3), 153.
      Knutson, J.C., et al. 1995. Endocrinology 136, 4749.
      Product Information
      CAS number54573-75-0
      FormWhite crystalline solid
      Hill FormulaC₂₈H₄₄O₂
      Chemical formulaC₂₈H₄₄O₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSVS2950000
      Safety Information
      R PhraseR: 28-63

      Very toxic if swallowed.
      Possible risk of harm to the unborn child.
      S PhraseS: 22-36/37/39-45

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      679100 0

      Documentation

      Vitamin D₂, 1α-Hydroxy- - CAS 54573-75-0 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Vitamin D₂, 1α-Hydroxy- - CAS 54573-75-0 - Calbiochem Analysenzertifikate

      TitelChargennummer
      679100

      Literatur

      Übersicht
      Coburn, J.W., et al. 1996. Nephrol. Dial. Transplant. 11 (Suppl. 3), 153.
      Knutson, J.C., et al. 1995. Endocrinology 136, 4749.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-September-2008 RFH
      Synonyms1α-OH-D₂
      DescriptionVitamin D2 analog with potential for the treatment of secondary hyperparathyroidism and metabolic bone disease. May be an effective and safer alternative to calcitriol (1α,25-dihydroxyvitamin D3, Cat. No. 679101) for suppressing PTH without causing hypercalcemia. Metabolized in vivo to the natural active dihydroxylated metabolite to vitamin D2, 1α,25-dihydroxyvitamin D2.
      FormWhite crystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number54573-75-0
      RTECSVS2950000
      Chemical formulaC₂₈H₄₄O₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityEthanol
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      ReferencesCoburn, J.W., et al. 1996. Nephrol. Dial. Transplant. 11 (Suppl. 3), 153.
      Knutson, J.C., et al. 1995. Endocrinology 136, 4749.