Millipore Sigma Vibrant Logo

579002 Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem

Tamoxifen, 4-Hydroxy-, (Z), CAS 68047-06-3, is a cell-permeable, active metabolite of Tamoxifen that is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.

SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: (Z)-4-Hydroxytamoxifen, 4-OH-TAM, Estrogen Receptor Signaling Regulator II

Primary Target: PKC
View Products on Sigmaaldrich.com
579002
  
Preis wird abgerufen...
Preis nicht abrufbar
Die Mindestmenge muss ein Vielfaches sein von
Maximum Quantity is
Bei Bestätigung Weitere Informationen
Sie haben () gespart
 
—
Bitte erfragen
—
Eingeschränkte Verfügbarkeit Eingeschränkte Verfügbarkeit
Lieferbar 
Produkt wurde eingestellt
Begrenzter Lagerbestand
Bestätigung der Verfügbarkeit erforderlich
    Restmenge: Angebot folgt
      Restmenge: Angebot folgt
      Bitte erfragen
      Kontakt zum Kundenservice
      Contact Customer Service

       

      Kontakt zum Kundenservice

      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      68047-06-3C₂₆H₂₉NO₂
      Description
      OverviewA cell-permeable, active metabolite of Tamoxifen (Cat. No. 579000) that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain. Also available as a 10 mM solution in EtOH (Cat. No. 508225).
      Catalogue Number579002
      Brand Family Calbiochem®
      Synonyms(Z)-4-Hydroxytamoxifen, 4-OH-TAM, Estrogen Receptor Signaling Regulator II
      References
      ReferencesGundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
      Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
      Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
      Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.
      Product Information
      CAS number68047-06-3
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₆H₂₉NO₂
      Chemical formulaC₂₆H₂₉NO₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      ApplicationTamoxifen, 4-Hydroxy-, (Z), CAS 68047-06-3, is a cell-permeable, active metabolite of Tamoxifen that is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.
      Biological Information
      Primary TargetPKC
      Purity≥99% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSSL1210000
      Safety Information
      R PhraseR: 22-45-60-61-64

      Harmful if swallowed.
      May cause cancer.
      May impair fertility.
      May cause harm to the unborn child.
      May cause harm to breastfed babies.
      S PhraseS: 36/37/39-45

      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      579002 0

      Documentation

      Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem Analysenzertifikate

      TitelChargennummer
      579002

      Literatur

      Übersicht
      Gundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
      Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
      Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
      Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.

      Broschüre

      Titel
      Caspases and other Apoptosis Related Tools Brochure
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-February-2012 RFH
      Synonyms(Z)-4-Hydroxytamoxifen, 4-OH-TAM, Estrogen Receptor Signaling Regulator II
      DescriptionA cell-permeable, active metabolite of Tamoxifen (Cat. No. 579000) that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.
      FormWhite solid
      CAS number68047-06-3
      RTECSSL1210000
      Chemical formulaC₂₆H₂₉NO₂
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityEthanol (20 mg/ml, heating may be required) or Methanol (10 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful & Carcinogenic / Teratogenic
      ReferencesGundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
      Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
      Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
      Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.