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05-23-3802 Sarafotoxin S6b, Atractaspsis engaddensis

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Synonyme: SRTX-b, CSCKDMTDKECLYFCHQDVIW

05-23-3802
  
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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      116303-65-2C₁₁₀H₁₅₉N₂₇O₃₄S₅
      Description
      Overview

      This product has been discontinued.

      Please refer to our complete listing of endothelin receptor agonists for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.






      Endothelin-related peptide that binds to the endothelin receptor in various tissues (Kd = 150 pM). Increases intracellular Ca2+ levels by activating ETA receptors. Exhibits vasoconstrictor activity and stimulates protein synthesis.
      Catalogue Number05-23-3802
      Brand Family Calbiochem®
      SynonymsSRTX-b, CSCKDMTDKECLYFCHQDVIW
      References
      ReferencesBacon, C.R., and Davenport, A.P. 1996. Br. J. Pharmacol. 117, 986.
      Bax, W.A., et al. 1994. Br. J. Pharmacol. 113, 1471.
      Koyama, Y., et al. 1993. Brain Res. 600, 81.
      Sugden, P.H., et al. 1993. Biochim. Biophys. Acta 1175, 327.
      Watanabe, C., et al. 1993. Br. J. Pharmacol. 108, 30.
      Marsault, R., et al. 1991. Am. J. Physiol. 261, C987.
      Product Information
      CAS number116303-65-2
      FormLyophilized
      FormulationSold on the basis of peptide content.
      Hill FormulaC₁₁₀H₁₅₉N₂₇O₃₄S₅
      Chemical formulaC₁₁₀H₁₅₉N₂₇O₃₄S₅
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Cys¹-Ser-Cys³-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys¹¹-Leu-Tyr-Phe-Cys¹⁵-His-Gln-Asp-Val-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      05-23-3802 0

      Documentation

      Sarafotoxin S6b, Atractaspsis engaddensis Analysenzertifikate

      TitelChargennummer
      05-23-3802

      Literatur

      Übersicht
      Bacon, C.R., and Davenport, A.P. 1996. Br. J. Pharmacol. 117, 986.
      Bax, W.A., et al. 1994. Br. J. Pharmacol. 113, 1471.
      Koyama, Y., et al. 1993. Brain Res. 600, 81.
      Sugden, P.H., et al. 1993. Biochim. Biophys. Acta 1175, 327.
      Watanabe, C., et al. 1993. Br. J. Pharmacol. 108, 30.
      Marsault, R., et al. 1991. Am. J. Physiol. 261, C987.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      SynonymsSRTX-b, CSCKDMTDKECLYFCHQDVIW
      DescriptionEndothelin-related peptide that binds to the endothelin receptor in various tissues (Kd = 150 pM). Increases intracellular Ca2+ levels by activating ETA receptors. Has vasoconstrictor activity and stimulates protein synthesis.
      FormLyophilized
      FormulationSold on the basis of peptide content.
      CAS number116303-65-2
      Chemical formulaC₁₁₀H₁₅₉N₂₇O₃₄S₅
      Peptide SequenceH-Cys¹-Ser-Cys³-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys¹¹-Leu-Tyr-Phe-Cys¹⁵-His-Gln-Asp-Val-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
      Purity≥97% by HPLC
      Solubility5% Acetic acid (1 mg/ml)
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Harmful
      ReferencesBacon, C.R., and Davenport, A.P. 1996. Br. J. Pharmacol. 117, 986.
      Bax, W.A., et al. 1994. Br. J. Pharmacol. 113, 1471.
      Koyama, Y., et al. 1993. Brain Res. 600, 81.
      Sugden, P.H., et al. 1993. Biochim. Biophys. Acta 1175, 327.
      Watanabe, C., et al. 1993. Br. J. Pharmacol. 108, 30.
      Marsault, R., et al. 1991. Am. J. Physiol. 261, C987.