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05-23-5501 Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem

Übersicht

Key Spec Table

CAS #Empirical Formula
52232-67-4C₁₈₁H₂₉₁N₅₅O₅₁S₂

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05-23-5501-1MG
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      Kst.-Ampulle 1 mg
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      Description
      OverviewN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
      Catalogue Number05-23-5501
      Brand Family Calbiochem®
      References
      ReferencesMatsui, H., et al. 1995. Am. J. Physiol. 268, R21.
      Dua, K., et al. 1994. Exp. Physiol. 79, 401.
      Product Information
      CAS number52232-67-4
      ATP CompetitiveN
      FormWhite to off-white lyophilized solid
      FormulationSupplied as an trifluoroacetate salt.
      Hill FormulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
      Chemical formulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
      ReversibleN
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Biological Information
      Primary TargetHomeostatic control of Ca2+ and phosphate metabolism
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide ContentY
      Peptide SequenceH-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Bestellnummer GTIN
      05-23-5501-1MG 04055977226850