Menge	Bestellnummer	Bestellinformationen	St./Pkg.	Listenpreis
			96-Well Plate

Menge	Bestellnummer	Bestellinformationen	St./Pkg.	Listenpreis
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

529570 PPM-18

PPM-18: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Analysenzertifikat
Literatur
Data Sheet

Synonyme: 2-Benzoylamino-1,4-naphthoquinone

Primary Target: iNOS

529570

Preis wird abgerufen...

Preis nicht abrufbar

Die Mindestmenge muss ein Vielfaches sein von

Maximum Quantity is

Bei Bestätigung

Sie haben () gespart

—

Bitte erfragen

—

Lieferbar

Produkt wurde eingestellt

Begrenzter Lagerbestand

Bestätigung der Verfügbarkeit erforderlich

Restmenge: Angebot folgt

Bitte erfragen

Kontakt zum Kundenservice

Contact Customer Service

Kontakt zum Kundenservice

Menge:

Bulk Size or Custom Request

Empfohlene Produkte

Übersicht

Replacement Information

Key Spec Table

CAS #	Empirical Formula
65240-86-0	C₁₇H₁₁NO₃

Description
Overview	This product has been discontinued. Please refer to our complete listing of nitric oxide synthase inhibitors for possible alternatives. A novel, cell-permeable, anti-inflammatory agent that inhibits the expression of inducible nitric oxide synthase (iNOS; IC₅₀ = ~ 5 µM). Acts by blocking the activation of NF-κB in vitro and in vivo. Does not directly affect the enzymatic activities of iNOS or eNOS.
Catalogue Number	529570
Brand Family	Calbiochem®
Synonyms	2-Benzoylamino-1,4-naphthoquinone

References
References	Davis, M.E., et al. 2004. J. Biol. Chem. 279, 163. Yu, S.M., et al. 1997. Biochem. J. 328, 363. Lien, J.-C., et al. 1996. Chem. Pharm. Bull. 44, 1181.

Product Information
CAS number	65240-86-0
Form	Yellow-orange solid
Hill Formula	C₁₇H₁₁NO₃
Chemical formula	C₁₇H₁₁NO₃
Structure formula Image

Applications

Biological Information
Primary Target	iNOS
Primary Target IC<sub>50</sub>	5 mM
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
Bestellnummer	GTIN
529570	0

Documentation

PPM-18 Analysenzertifikate

Titel	Chargennummer
529570	Chargen-Nr.

Literatur

Übersicht
Davis, M.E., et al. 2004. J. Biol. Chem. 279, 163. Yu, S.M., et al. 1997. Biochem. J. 328, 363. Lien, J.-C., et al. 1996. Chem. Pharm. Bull. 44, 1181.

Datenblatt

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	07-April-2008 RFH
Synonyms	2-Benzoylamino-1,4-naphthoquinone
Description	A cell-permeable naphthoquinone derivative that inhibits the expression of iNOS (IC₅₀ ~5 µM) by blocking the activation of NF-κB in vitro and in vivo. Does not directly affect the enzymatic activities of iNOS or eNOS. Also prevents the dissociation of NF-κB/IκB-α complex and acts as a potent anti-inflammatory and anti-sepsis agent.
Form	Yellow-orange solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	65240-86-0
Chemical formula	C₁₇H₁₁NO₃
Structure formula
Purity	≥97% by HPLC
Solubility	DMSO (5 mg/ml) or CH₃CN (5 mg/ml)
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Davis, M.E., et al. 2004. J. Biol. Chem. 279, 163. Yu, S.M., et al. 1997. Biochem. J. 328, 363. Lien, J.-C., et al. 1996. Chem. Pharm. Bull. 44, 1181.

Kategorien

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > NF-κB Activation

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Nitric Oxide and Oxidative Stress > Nitric Oxide Synthase (NOS) Inhibitors

Das Produkt wurde in Ihre Bestellung aufgenommen