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505761 PPADS

PPADS: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: P2 Purinergic Receptor Antagonist, PPADS

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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      192575-19-2C₁₄H₁₀N₃Na₄O₁₂PS₂
      Description
      Overview

      This product has been discontinued.



      A selective P2 purinergic receptor antagonist that block ATP responses at both pre- and post-junctional sites (IC50 = 2.5 µM). Shown to antagonize P2x-purinoceptor-mediated responses in the rabbit urinary bladder. Acts on P2Y, but not on P2U receptors in rat mesenteric arteries. Induces a gradual decline in ATP-activated current to a steady state.

      Please note that the molecular weight for this compound is batch-specific due to variable water content.
      Catalogue Number505761
      Brand Family Calbiochem®
      SynonymsP2 Purinergic Receptor Antagonist, PPADS
      References
      ReferencesLi. C. 2000. J. Neurophysiol. 83, 2533.
      Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.
      Product Information
      CAS number192575-19-2
      FormOrange solid
      Hill FormulaC₁₄H₁₀N₃Na₄O₁₂PS₂
      Chemical formulaC₁₄H₁₀N₃Na₄O₁₂PS₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target IC<sub>50</sub>2.5 µ
      Purity≥90 by 1H NMR
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      505761 0

      Documentation

      PPADS SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Literatur

      Übersicht
      Li. C. 2000. J. Neurophysiol. 83, 2533.
      Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-April-2014 JSW
      SynonymsP2 Purinergic Receptor Antagonist, PPADS
      DescriptionA selective P2 purinergic receptor antagonist that block ATP responses at both pre- and post-junctional sites (IC50 = 2.5 µM). Shown to antagonize P2x-purinoceptor-mediated responses in the rabbit urinary bladder. Acts on P2Y, but not on P2U receptors in rat mesenteric arteries. Induces a gradual decline in ATP-activated current to a steady state.
      FormOrange solid
      CAS number192575-19-2
      Chemical formulaC₁₄H₁₀N₃Na₄O₁₂PS₂
      Structure formulaStructure formula
      Purity≥90 by 1H NMR
      SolubilityH₂O (100 mM)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLi. C. 2000. J. Neurophysiol. 83, 2533.
      Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.