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529574 PP3 - CAS 5334-30-5 - Calbiochem

PP3, CAS 5334-30-5, is a negative control for the Src family protein tyrosine kinase inhibitor PP2 (Cat. No. 529573). However, it inhibits the activity of EGFR kinase (IC50 = 2.7 µM).

PP3 - CAS 5334-30-5 - Calbiochem: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: 4-Amino-7-phenylpyrazol[3,4-d]pyrimidine

Primary Target: EGFR kinase
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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      5334-30-5C₁₁H₉N₅
      Description
      Overview

      This product has been discontinued.



      A negative control for the Src family protein tyrosine kinase inhibitor PP2 (Cat. No. 529573). However, it inhibits the activity of EGFR kinase (IC50 = 2.7 µM).

      Catalogue Number529574
      Brand Family Calbiochem®
      Synonyms4-Amino-7-phenylpyrazol[3,4-d]pyrimidine
      References
      ReferencesTraxler, P., et al. 1997. J. Med. Chem. 40, 3601.
      Product Information
      CAS number5334-30-5
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₁₁H₉N₅
      Chemical formulaC₁₁H₉N₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationPP3, CAS 5334-30-5, is a negative control for the Src family protein tyrosine kinase inhibitor PP2 (Cat. No. 529573). However, it inhibits the activity of EGFR kinase (IC50 = 2.7 µM).
      Biological Information
      Primary TargetEGFR kinase
      Primary Target IC<sub>50</sub>2.7 µM against EGFR kinase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      529574 0

      Documentation

      PP3 - CAS 5334-30-5 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      PP3 - CAS 5334-30-5 - Calbiochem Analysenzertifikate

      TitelChargennummer
      529574

      Literatur

      Übersicht
      Traxler, P., et al. 1997. J. Med. Chem. 40, 3601.

      Broschüre

      Titel
      Bulk Product Guide

      Literaturstellen

      Titel
    • Ellen J. Tisdale and Cristina R. Artalejo. 2006. Journal of Biological Chemistry 281, 8436.
      		•
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-August-2008 RFH
      Synonyms4-Amino-7-phenylpyrazol[3,4-d]pyrimidine
      DescriptionA negative control for the Src family of protein tyrosine kinase inhibitor PP2 (Cat. No. 529573); however, it inhibits the activity of EGFR kinase (IC50 = 2.7 µM).
      FormOff-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number5334-30-5
      Chemical formulaC₁₁H₉N₅
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO. Further dilute with aqueous buffers just prior to use.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
      Toxicity Standard Handling
      ReferencesTraxler, P., et al. 1997. J. Med. Chem. 40, 3601.
      Citation
    • Ellen J. Tisdale and Cristina R. Artalejo. 2006. Journal of Biological Chemistry 281, 8436.
      		•