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539684 PKA Inhibitor 6-22 Amide - CAS 121932-06-7 - Calbiochem

The PKA Inhibitor 6-22 Amide, also referenced under CAS 121932-06-7, controls the biological activity of PKA. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: PKI 6-22 Amide, TYADFIASGRTGRRNAI-NH₂, Protein Kinase A Inhibitor 6-22 Amide, PKA Inhibitor VIII

Primary Target: PKA
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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      121932-06-7C₈₀H₁₃₀N₂₈O₂₄
      Description
      OverviewA potent and competitive inhibitor of protein kinase A (Ki = 1.7 nM).
      Catalogue Number539684
      Brand Family Calbiochem®
      SynonymsPKI 6-22 Amide, TYADFIASGRTGRRNAI-NH₂, Protein Kinase A Inhibitor 6-22 Amide, PKA Inhibitor VIII
      References
      ReferencesGlass, D.B., et al. 1989. J. Biol. Chem. 264, 8802.
      Kemp, B.E., et al. 1988. Methods Enzymol. 159, 173.
      Product Information
      CAS number121932-06-7
      ATP CompetitiveN
      FormSolid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₈₀H₁₃₀N₂₈O₂₄
      Chemical formulaC₈₀H₁₃₀N₂₈O₂₄
      Hygroscopic Hygroscopic
      ReversibleN
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKA
      Primary Target K<sub>i</sub> 1.7 nM against protein kinase A
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide ContentY
      Peptide SequenceH-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      539684 0

      Documentation

      PKA Inhibitor 6-22 Amide - CAS 121932-06-7 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      PKA Inhibitor 6-22 Amide - CAS 121932-06-7 - Calbiochem Analysenzertifikate

      TitelChargennummer
      539684

      Literatur

      Übersicht
      Glass, D.B., et al. 1989. J. Biol. Chem. 264, 8802.
      Kemp, B.E., et al. 1988. Methods Enzymol. 159, 173.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-September-2008 RFH
      SynonymsPKI 6-22 Amide, TYADFIASGRTGRRNAI-NH₂, Protein Kinase A Inhibitor 6-22 Amide, PKA Inhibitor VIII
      DescriptionA potent and competitive inhibitor of PKA (Ki = 1.7 nM).
      FormSolid
      FormulationSupplied as a trifluoroacetate salt.
      CAS number121932-06-7
      Chemical formulaC₈₀H₁₃₀N₂₈O₂₄
      Peptide SequenceH-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH₂
      Purity≥97% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGlass, D.B., et al. 1989. J. Biol. Chem. 264, 8802.
      Kemp, B.E., et al. 1988. Methods Enzymol. 159, 173.