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539744 InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I - Calbiochem

539744
  
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      Übersicht

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      The InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I consists of 80, well-characterized, cell-permeable, potent and reversible protein kinase inhibitors; the majority of which are ATP-competitive. They are supplied in a convenient 96-well plate format at a concentration of 10 mM in DMSO. The inhibitors in this library will be useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications.

      Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
      Catalogue Number539744
      Brand Family Calbiochem®
      Application Data

      ** Total higher than 80, as some inhibitors target kinases in other branches as well TK: Tyrosine Kinase Group AGC: PKA, PKG, and PKC Containing Group TKL: Tyrosine Kinase-Like Group
      References
      Product Information
      Form96-well plate
      FormulationAll of the inhibitors, except for one, are supplied at a concentration of 10 mM in DMSO (50 µl/well).
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38-68

      Irritating to eyes and skin.
      Possible risks of irreversible effects.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Harmful
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      539744 0

      Documentation

      InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I - Calbiochem Analysenzertifikate

      TitelChargennummer
      539744

      Literaturstellen

      Titel
    • Hou, P., et al. 2013. Science 341, 651.
    • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
    • Yinghong Gao, et al. 2013. Biochem. J. in press.
    • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Wakatsuki, S., 2011. Nature Cell Biol. 13, 1415.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Donovi, D., et al. 2010. Biochem Soc Trans. 38, 1067.
    • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
    • Li, Tao, et al. 2010. Anal. Chem. 82, 3067.
    • Cameron A. J. M., et al. 2009., Nature Structural & Molecular Biology 16, 624.
    • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 132 2518.
    • Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-September-2012 JSW
      Application Data

      ** Total higher than 80, as some inhibitors target kinases in other branches as well TK: Tyrosine Kinase Group AGC: PKA, PKG, and PKC Containing Group TKL: Tyrosine Kinase-Like Group
      DescriptionThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I consists of 80, well-characterized protein kinase inhibitors, the majority of which are cell-permeable and ATP-competitive. The library is useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications. Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
      Form96-well plate
      FormulationAll of the inhibitors, except for one, are supplied at a concentration of 10 mM in DMSO (50 µl/well).
      Intert gas (Yes/No) Packaged under inert gas
      Storage Protect from light
      ≤ -70°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
      Toxicity Harmful
      Citation
    • Hou, P., et al. 2013. Science 341, 651.
    • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
    • Yinghong Gao, et al. 2013. Biochem. J. in press.
    • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Wakatsuki, S., 2011. Nature Cell Biol. 13, 1415.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Donovi, D., et al. 2010. Biochem Soc Trans. 38, 1067.
    • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
    • Li, Tao, et al. 2010. Anal. Chem. 82, 3067.
    • Cameron A. J. M., et al. 2009., Nature Structural & Molecular Biology 16, 624.
    • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 132 2518.